Katarzyna Tutak, Izabela Broniarek ... Krzysztof Sobczak
Identification of ribosomal proteins RPS26 and RPS25, along with chaperone TSR2, as new important modifiers in the noncanonical translation process linked to fragile X premutation disorders.
AARS2 safeguards cardiomyocytes against ischemic injury by modulating PKM2-driven energy metabolism, revealing the AARS2-PKM2 axis as a previously unrecognized cardioprotective pathway in myocardial infarction.
A cross-talk is revealed between two branches of metabolisms, amino acid limitation suppressing fatty acid biosynthesis, via posttranslational modifications of an enzyme involved in fatty acid biosynthesis.
MARK2-mediated phosphorylation of CAMSAP2 dynamically controls Golgi orientation by altering microtubule anchoring and polarity during directional cell migration.
Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.
