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The Tsr2 carrier protein connects the nuclear import machinery with the ribosome assembly pathway.

microRNAs can serve as a surveillance system to repress nonsense mRNAs by recognizing miRNA-responsive elements in the open reading frame region downstream of the premature termination codon.

Controlling cell cycle progression in a developing embryo directly depends on de novo histone supply and a specialized surveillance mechanism for nucleosome assembly.

The Fat/Dachsous/Four-jointed (Ft/Ds/Fj) system provides a spatial signal to organize core PCP proteins via the polarization of microtubules.

Using linked TOG domains that each bind a curved conformation of αβ-tubulin, a microtubule polymerase catalyzes fast elongation by concentrating αβ-tubulin near the polymer end.

The F-box protein Fbxl7 is a direct effector of the protocadherin Fat and functions in downstream pathways that regulate tissue shape and size.

A previously unappreciated histone methylation pathway helps limit DNA double-strand break formation and recombination in heterochromatin during meiosis.

The ability of calcium waves to exert different effects on calcineurin activity depending on subcellular location is mediated by the distribution of calmodulin.

Unlike other cytoskeletal motors that produce torque in a specific direction, cytoplasmic dynein generates torque in either direction, resulting in bidirectional helical motility along microtubules.