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Page 34 of 314
    1. Cell Biology
    2. Neuroscience

    Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

    Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
    Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
    1. Cell Biology

    Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells

    Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cancer Biology
    2. Cell Biology

    mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated ubiquitination of eIF4A1 in cancer cells

    Dongyue Jiao, Huiru Sun ... Kun Gao
    Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MEMO1 binds iron and modulates iron homeostasis in cancer cells

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    Cancer metastasis modulator MEMO1 binds iron and is involved in regulating iron homeostasis in cancer cells.
    1. Cell Biology

    Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile

    Yoko Nakai-Futatsugi, Jianshi Jin ... Masayo Takahashi
    Pigmentation that confers protective function of RPE is not underlaid by a specific gene expression profile, reviled by microscopic imaging together with single-cell RNA sequencing.
    1. Cell Biology

    Cardiac neurons expressing a glucagon-like receptor mediate cardiac arrhythmia induced by high-fat diet in Drosophila

    Yunpo Zhao, Jianli Duan ... Zhe Han
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Synapsin E-domain is essential for α-synuclein function

    Alexandra Stavsky, Leonardo A Parra-Rivas ... Daniel Gitler
    Alpha-synuclein binding to the synapsin E-domain is essential and sufficient for their cooperation in attenuating synaptic-vesicle trafficking and neurotransmission.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

    Carola Maria Morell, Samantha Grace Tilson ... Ludovic Vallier
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function

    Rita De Gasperi, Laszlo Csernoch ... Christopher P Cardozo
    Genetic reduction of Numb or Numb/Nubl is linked to deterioration of the Septin cytoskeleton and suggests cytoskeletal abnormalities are the consequences of and contribute to age-related changes in skeletal muscle.
    1. Cell Biology

    JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease

    Yunpo Zhao, Jianli Duan ... Zhe Han
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Solid
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