Browse our latest Cell Biology articles

Mfn2 depletion upregulates cytosolic Ca²⁺ in mouse fibroblast cells, leading to RhoA and nonmuscle myosin II overactivation and a prominent peripheral actin band structure, which is dependent on the contractile force on the cell–substrate interface.

A newly established reversible model of membrane departitioning and repartitioning in bacteria uncovers the role of a cell wall synthase in regulating membrane partitioning.

Single-cell data on cell signaling responses to nutrient variation enable quantitative models of cellular control over protein synthesis, formalizing the concept of mTOR as a homeostatic controller of cellular metabolism.

Analysis of islet calcium oscillation responses will provide the field with a resource with which to determine the strain of interest for their specific islet biology questions.

Mitochondrial quality control in the germline is mediated by regulators of both programmed cell death and the aging program.

Engineered mesenchymal stem cells (MSCs) could produce mutant β-galactosidase and trigger nitric oxide (NO) release when the NO prodrug is systemically administered, which can achieve NO release in a precise spatiotemporal manner and augment the therapeutic efficiency of MSCs.

The previously uncharacterized, evolutionarily conserved FAM104 proteins VCF1/2 stimulate the nuclear import of p97/VCP, with their absence causing reduced nuclear p97/VCP levels, slow growth, and hypersensitivity to pharmacological inhibition of p97/VCP.

A novel Caenorhabditis elegans model that secretes human amyloid beta forms aggregates in the extracellular matrix, which are removed by activation of extracellular matrix dynamics.