Browse our latest Cell Biology articles

SLIT2, a prototypic neuro-repellent, spatiotemporally coordinates host defense against Staphylococcus aureus infection by priming neutrophils and stimulating release of reactive oxygen species and secondary and tertiary granules, potently enhancing bactericidal actions of neutrophils.

Fungal hyphae constantly undergo signal oscillations, comparable to a cell 'monologue' until they meet another hypha with which they then coordinate signal oscillations and transit into a cell-to-cell dialogue.

An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.

Mitochondrial functional and structural defects caused by PARL deficiency lead to arrested spermatogenesis and germ cell ferroptosis.

The apical polarity protein CRB3 is crucial for regulating vesicle trafficking in γ-tubulin ring complex assembly during ciliogenesis and cilium-related Hedgehog and Wnt signaling pathways in tumorigenesis.

Combining micropatterning, traction force microscopy, and optogenetics, it is shown that epithelial cells actively respond to mechanical signals from neighboring cells.

Analysis of inositol pyrophosphate dynamics upon inorganic phosphate (P_i) starvation identifies 1,5-IP₈ as the inositol pyrophosphate isomer signaling P_i sufficiency to the SPX domain of Pho81 that controls the transcriptional P_i starvation program.

Gene function studies confirmed that the BATF-PD1 axis and BATF-IL27 axis are regulatory factor for lipid accumulation in hepatocytes and adipocytes.

Targeted recruitment of protein kinase A subunits enables distinctive regulation of the functional expression of a potassium channel depending on whether the enzyme is targeted to a pore-forming or auxiliary subunit.