Browse our latest Cell Biology articles

Page 66 of 315
    1. Cell Biology
    2. Developmental Biology

    Control of craniofacial development by the collagen receptor, discoidin domain receptor 2

    Fatma F Mohamed, Chunxi Ge ... Renny T Franceschi
    Discoidin domain receptor 2 controls craniofacial morphology by acting in skeletal progenitor cells and chondrocytes to control collagen matrix organization, chondrocyte polarity, and growth.
    1. Cell Biology

    Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila

    Rouba Jneid, Rihab Loudhaief ... Armel Gallet
    Bacillus thuringiensis crystalline toxins used as microbial pesticides disrupt the homeostasis of intestinal cells of the non-target Drosophila melanogaster.
    1. Cell Biology

    Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

    Maria-Bernadette Madel, Julia Halper ... Claudine Blin-Wakkach
    Transcriptomic comparison of inflammatory and steady-state osteoclasts reveals differences in their ability to sense their environment, which makes it possible to selectively inhibit inflammatory osteoclastogenesis and reduce bone loss in osteoporosis.
    1. Cell Biology

    Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis

    Chunxiu Du, Hu Xu ... Xiaoyan Zhang
    The neutral amino acid transporter SLC38A2 is an essential protective factor for renal medulla during urine concentration.
    1. Cell Biology

    The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5

    Ryota Miyashita, Atsuya Nishiyama ... Makoto Nakanishi
    The cooperative action of PAF15 deubiquitylation by USP7 and its dissociation from chromatin by ATAD5 regulates proper PAF15Ub2 signaling termination, which is important for replication and maintenance of DNA methylation.
    1. Cell Biology
    2. Physics of Living Systems

    Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia

    Christa Ringers, Stephan Bialonski ... Nathalie Jurisch-Yaksi
    Novel frequency-based analysis and computation modeling of cilia carpets reveals that tissue-scale metachronal coordination of cilia can arise even in the absence of global synchronization.
    1. Cell Biology
    2. Neuroscience

    Pericytes control vascular stability and auditory spiral ganglion neuron survival

    Yunpei Zhang, Lingling Neng ... Xiaorui Shi
    Pericytes in the adult ear are critical for vascular stability and spiral ganglion neuron health.
    1. Cell Biology
    2. Neuroscience

    Protein composition of axonal dopamine release sites in the striatum

    Lauren Kershberg, Aditi Banerjee, Pascal S Kaeser
    Proximity proteomics combined with mouse genetics are used to assess the composition of active zone-like sites for dopamine release and reveal that the scaffolding protein RIM organizes these sites.
    1. Cell Biology

    A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

    Jake P Mann, Xiaowen Duan ... David B Savage
    The p.Arg707Trp mutation in Mfn2 causes adipose-specific activation of the integrated stress response, which lowers secretion of adipokines.
    1. Cell Biology
    2. Medicine

    Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study

    Avner Ehrlich, Konstantinos Ioannidis ... Yaakov Nahmias
    Human metabolism-focused screens reveal clinically promising interventional strategies and repurposing targets to treat COVID-19.