Browse our latest Cell Biology articles

Page 69 of 318
    1. Cell Biology

    Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis

    Chunxiu Du, Hu Xu ... Xiaoyan Zhang
    The neutral amino acid transporter SLC38A2 is an essential protective factor for renal medulla during urine concentration.
    1. Cell Biology

    The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5

    Ryota Miyashita, Atsuya Nishiyama ... Makoto Nakanishi
    The cooperative action of PAF15 deubiquitylation by USP7 and its dissociation from chromatin by ATAD5 regulates proper PAF15Ub2 signaling termination, which is important for replication and maintenance of DNA methylation.
    1. Cell Biology
    2. Physics of Living Systems

    Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia

    Christa Ringers, Stephan Bialonski ... Nathalie Jurisch-Yaksi
    Novel frequency-based analysis and computation modeling of cilia carpets reveals that tissue-scale metachronal coordination of cilia can arise even in the absence of global synchronization.
    1. Cell Biology
    2. Neuroscience

    Pericytes control vascular stability and auditory spiral ganglion neuron survival

    Yunpei Zhang, Lingling Neng ... Xiaorui Shi
    Pericytes in the adult ear are critical for vascular stability and spiral ganglion neuron health.
    1. Cell Biology
    2. Neuroscience

    Protein composition of axonal dopamine release sites in the striatum

    Lauren Kershberg, Aditi Banerjee, Pascal S Kaeser
    Proximity proteomics combined with mouse genetics are used to assess the composition of active zone-like sites for dopamine release and reveal that the scaffolding protein RIM organizes these sites.
    1. Cell Biology

    A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

    Jake P Mann, Xiaowen Duan ... David B Savage
    The p.Arg707Trp mutation in Mfn2 causes adipose-specific activation of the integrated stress response, which lowers secretion of adipokines.
    1. Cell Biology
    2. Medicine

    Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study

    Avner Ehrlich, Konstantinos Ioannidis ... Yaakov Nahmias
    Human metabolism-focused screens reveal clinically promising interventional strategies and repurposing targets to treat COVID-19.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

    Marco Caligaris, Raffaele Nicastro ... Claudio De Virgilio
    Discovery of new Snf1/AMPK targets in the TORC1 pathway highlights the complex, multilayered crosstalk between major signaling pathways in the regulation of nutrient deprivation sensing.
    1. Cell Biology
    2. Physics of Living Systems

    Condensates: When fixation creates fiction

    Judith Miné-Hattab
    A chemical regularly used to image cells can dramatically alter the way cellular compartments called condensates look under the microscope.
    Version of Record
    Insight
    1. Cell Biology

    Impaired iron recycling from erythrocytes is an early hallmark of aging

    Patryk Slusarczyk, Pratik Kumar Mandal ... Katarzyna Mleczko-Sanecka
    A decline in iron-recycling functions of the splenic red pulp macrophages early during aging is driven by iron loading and involves their damage and a loss in red blood cell clearance capacity.