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The hagfish slime glands, which produce a large volume of defensive slime within 0.4 s by ejecting threads and mucus into seawater, evolved from cells and genes expressed in the skin.

Gene knockout in cell lines and mice reveal that store-operated calcium entry is synergistically mediated by Orai1 and Orai3 channel proteins in B cells and is important for signaling to the nucleus and metabolic activity in response to antigenic stimulation.

Genetic and cytological analyses reveal a regulatory circuit that controls a key cell cycle transition during meiosis and mediates feedback regulation in response to meiotic defects.

Implementation and characterisation of plasma-focused ion beams for volumetric imaging of cryogenically preserved cells and tissues for ultrastructural examination in their native state.

Calmodulin mediates in the protective augmentation of K_V7-currents in response to oxidative stress in a calcium-dependent manner by an unconventional signaling mechanism.

TIRF microscopy in living pancreatic beta cells lacking one or two of Rab27 effectors and the exocyst components reveals how each molecule functions in sequence or in parallel in multiple redundant paths and rate-limiting processes in granule exocytosis.

Histone methylation patterns may differ depending on the enzymatic source of the methyl donor S-adenosylmethionine, suggesting the biological effects of low SAM may affect methylation targets in different ways, depending on the synthase producing it.

Discoidin domain receptor 2 controls craniofacial morphology by acting in skeletal progenitor cells and chondrocytes to control collagen matrix organization, chondrocyte polarity, and growth.

Bacillus thuringiensis crystalline toxins used as microbial pesticides disrupt the homeostasis of intestinal cells of the non-target Drosophila melanogaster.

Transcriptomic comparison of inflammatory and steady-state osteoclasts reveals differences in their ability to sense their environment, which makes it possible to selectively inhibit inflammatory osteoclastogenesis and reduce bone loss in osteoporosis.