Browse our latest Cell Biology articles

Page 97 of 315
    1. Cell Biology
    2. Neuroscience

    Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria

    Chen Ding, Youjun Wu ... Marc Hammarlund
    Axon degeneration due to loss of mitochondria is suppressed by CaMKII activity and MAP kinase signaling.
    1. Cell Biology
    2. Developmental Biology

    Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

    Jialing Qi, Annegret Rittershaus ... Christian SM Helker
    Apelin signaling-dependent endocardial protrusions promote cardiac trabeculation through Nrg/ErbB/Erk signaling in zebrafish.
    1. Cell Biology
    2. Neuroscience

    Tadr is an axonal histidine transporter required for visual neurotransmission in Drosophila

    Yongchao Han, Lei Peng, Tao Wang
    TADR (torn and diminished rhabdomeres)-dependent histidine transporting is required for de novo synthesis of histamine and for maintaining synaptic transmission of photoreceptor neurons in Drosophila.
    1. Cancer Biology
    2. Cell Biology

    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

    Deborah Fanfone, Zhichong Wu ... Gabriel Ichim
    A biomechanical approach inducing confined cell migration reveals that mechanical stress has a profound effect on cancer cell survival.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling

    Naser Nasrollahzadeh, Peyman Karami ... Dominique P Pioletti
    The loading-induced temperature evolution phenomenon in the knee joint modulates chondrogenic cells response to loading and accordingly opens a new paradigm that is coined 'thermo-mechanobiology'.
    1. Cell Biology
    2. Developmental Biology

    A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary

    Wen Lu, Margot Lakonishok ... Vladimir I Gelfand
    Cortical dynein performs bulk cytoplasmic transport by gliding microtubules along the cell cortex and through the ring canals to the oocyte.
    1. Cancer Biology
    2. Cell Biology

    Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells

    Alejandro La Greca, Nicolás Bellora ... Patricia Saragüeta
    Binding of progesterone receptor and transcription factor PAX2 to pre-assembled permissive chromatin compartments regulates endometrial cancer gene expression under estrogenic conditions.
    1. Cell Biology

    A cellular and molecular atlas reveals the basis of chytrid development

    Davis Laundon, Nathan Chrismas ... Michael Cunliffe
    Three-dimensional cell modelling, lipid analysis, transcriptomics, and live-cell imaging reveal biological insights in to the key stages of the chytrid fungus life cycle.
    1. Cell Biology

    Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1

    Katarzyna Szymanska, Karsten Boldt ... Colin A Johnson
    Interacting MKS1 and UBE2E1 regulate canonical Wnt signaling through modulation of beta-catenin levels at the base of primary cilium, providing new insights into ciliopathy disease mechanisms.
    1. Cell Biology
    2. Developmental Biology

    Pathway-specific effects of ADSL deficiency on neurodevelopment

    Ilaria Dutto, Julian Gerhards ... Travis H Stracker
    Analysis of adenylosuccinate lyase (ADSL) deficiency in multiple experimental systems reveals cell and organismal phenotypes and impaired neurodevelopment due to the attenuation of ADSL's roles in distinct pathways.