Browse our latest Computational and Systems Biology articles

Page 5 of 128
    1. Computational and Systems Biology
    2. Medicine

    Global molecular landscape of early MASLD progression in human obesity

    Qing Zhao, William De Nardo ... Philipp Kaldis
    GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.
    1. Computational and Systems Biology
    2. Cancer Biology

    Systematic Analysis of Network-driven Adaptive Resistance to CDK4/6 and Estrogen Receptor Inhibition using Meta-Dynamic Network Modelling

    Anthony Hart, Sung-Young Shin, Lan K Nguyen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Policy-Gradient Reinforcement Learning as a General Theory of Practice-Based Motor Skill Learning

    Adrian M Haith
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    High performance sorting of motor unit action potentials with EMUsort

    Sean O’Connell, Jonathan A Michaels ... Chethan Pandarinath
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    Self-association enhances early attentional selection through automatic prioritization of socially salient signals

    Meike Scheller, Jan Tünnermann ... Jie Sui
    Self-related information automatically modulates early attentional selection into awareness through mechanisms distinct from physical salience, revealing an obligatory, individualized self-prioritization at the gateway to perception.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression

    Jie Lin, Yujian Wen ... Hao Zhu
    Compared with human-specific transcriptional factors, human-specific lncRNAs identified upon human lncRNAs’ orthologs in mammals have greatly evolved DNA-binding sites in archaic and modern humans in genes determining human traits.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations

    Luke J Dillard, Gina Calabrese ... Charles Farber
    Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles in the development of osteoporosis.
    1. Neuroscience
    2. Computational and Systems Biology

    Miniscope Processing Suite (MPS): An Intuitive, No-Code, Scalable Pipeline for Long-Duration Calcium Imaging

    Ari Peden-Asarch, Meredith Weinstock ... John F Neumaier
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix H Medema
    Automated detection of metallophore biosynthesis reveals that metal-chelating non-ribosomal peptides are widespread, chemically diverse, and deeply rooted in bacterial evolution.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    An interpretable neural network unveils higher-order epistasis in large protein sequence-function relationships

    Palash Sethi, Juannan Zhou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
Newer articles Older articles