Browse our latest Computational and Systems Biology articles

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    1. Cancer Biology
    2. Computational and Systems Biology

    BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

    Emilio Rios-Jimenez, Anoek Zomer ... Maria Alieva
    BEHAV3D Tumor Profiler enables researchers without computational expertise to uncover heterogeneous cell behaviors and explore their relationships with microenvironmental features in intravital microscopy data.
    1. Computational and Systems Biology

    A network regularized linear model to infer spatial expression pattern for single cell

    Chaohao Gu, Hu Chen, Zhandong Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Absence of Systematic Effects of Internalizing Psychopathology on Learning Under Uncertainty

    Muhammad H Satti, Katharina Wille ... Rasmus Bruckner
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology

    TrueProbes: Quantitative Single-Molecule RNA-FISH Probe Design Improves RNA Detection

    Jason J Hughes, Benjamin K Kesler ... Gregor Neuert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Deep Neural Networks to Register and Annotate Cells in Moving and Deforming Nervous Systems

    Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pan-tissue transcriptome analysis reveals sex-dimorphic human aging

    Siqi Wang, Danyue Dong ... Zefeng Wang
    Widespread sex-dimorphic transcriptomic changes during human aging in pan-tissues scale reveal distinct molecular aging trajectories and potential links to age-related disease vulnerability.
    1. Epidemiology and Global Health
    2. Computational and Systems Biology

    Refining uncertainty about the TAK-003 dengue vaccine with a multi-level model of clinical efficacy trial data

    Manar Alkuzweny, Guido España, T Alex Perkins
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Comparing the outputs of intramural and extramural grants funded by National Institutes of Health

    Xiang Zheng, Qiyao Yang ... B Ian Hutchins
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Squidly: Enzyme Catalytic Residue Prediction Harnessing a Biology-Informed Contrastive Learning Framework

    William JF Rieger, Mikael Boden ... Ariane Mora
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

    Darren Wethington, Saeed Ahmad ... Jayajit Das
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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