Hélène Vantomme, Valentin Quiniou ... David Klatzmann
Sex-specific biases in thymic T cell receptor selection enrich female CD8 T cell repertoires for autoimmunity-associated self-antigens, helping explain women’s increased susceptibility to autoimmune diseases.
Sebastián Cruz-Gonzalez, Ogechukwu Okpala ... John A Capra
DNA-methylation-based predictors of biological age often fail to generalize across human populations, limiting their utility as biomarkers of aging and disease.
Jeevan Tewari, Benjamin W Dahl ... Jeffrey J Saucerman
Current general-purpose large language models generate signaling and metabolic networks with only modest accuracy relative to manually curated network models.
Fundamental distinctions in the extracellular signatures of active-dendritic chemical and electrical synapses necessitate a revision of conventional interpretations of local field potentials centered on chemical synapses.