Browse our latest Computational and Systems Biology articles

Page 6 of 121
    1. Computational and Systems Biology

    A network regularized linear model to infer spatial expression pattern for single cell

    Chaohao Gu, Hu Chen, Zhandong Liu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology

    Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms

    George N Bendzunas, Dominic P Byrne ... Natarajan Kannan
    Characterization of redox-active cysteines illuminates the understudied regulatory mechanisms of brain-selective kinases.
    1. Neuroscience
    2. Computational and Systems Biology

    Olfactory combinatorial coding supports risk-reward decision making in C. elegans

    Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Ecology
    2. Computational and Systems Biology

    How bats exit a crowded colony when relying on echolocation only - a modeling approach

    Omer Mazar, Yossi Yovel
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Fast and slow synaptic plasticity enables concurrent control and learning

    Brendan A Bicknell, Peter E Latham
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Loss of CTRP10 results in female obesity with preserved metabolic health

    Fangluo Chen, Dylan C Sarver ... G William Wong
    Mice lacking the secreted hormone, CTRP10, represent a unique female model of obesity with preserved metabolic health, highlighting sex-specific mechanisms that uncouple obesity from metabolic dysfunction.
    1. Computational and Systems Biology

    Generative modeling for RNA splicing predictions and design

    Di Wu, Natalie Maus ... Yoseph Barash
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Thrifty wide-context models of B cell receptor somatic hypermutation

    Kevin Sung, Mackenzie M Johnson ... Frederick A Matsen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology

    Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging

    Huiyong Cheng, Dawson Miller ... Qiuying Chen
    A novel R ratiometric imaging tool provides enhanced knowledge obtained from conventional spatial data profiling technologies.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Exploring the repository of de novo-designed bifunctional antimicrobial peptides through deep learning

    Ruihan Dong, Rongrong Liu ... Cheng Zhu
    Peptides designed by artificial intelligence restrict both drug-resistant bacteria and rapidly evolving viruses.