Browse our latest Developmental Biology articles

Page 12 of 215
    1. Developmental Biology
    2. Physics of Living Systems

    Spectral decomposition unlocks ascidian morphogenesis

    Joel Dokmegang, Emmanuel Faure ... Madhav Mani
    The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.
    1. Developmental Biology

    BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus

    Guozhu Ning, Yu Lin ... Qiang Wang
    BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.
    1. Developmental Biology
    2. Neuroscience

    Activity-dependent synapse elimination requires caspase-3 activation

    Zhou Yu, Andrian Gutu ... Erin K O'Shea
    Caspase-3 activation links synapse weakening to synapse elimination.
    1. Developmental Biology
    2. Neuroscience

    A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila ventral nerve cord

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.
    1. Developmental Biology

    Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

    Pengzhen Dong, Yue Li ... Hai Huang
    Long-range communication between neighboring organs orchestrates the disciplined migration of stem cells.
    1. Developmental Biology

    Oviductin sets the species-specificity of the mammalian zona pellucida

    Daniel de la Fuente, Maria Maroto ... Alfonso Gutierrez-Adan
    The oocyte zona pellucida needs to interact with an oviduct protein called OVGP1 to ensure that only sperm from the same species can fertilize the egg.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Linage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors

    William M Salvidge, Chris Brimson ... Christopher RL Thompson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology

    The integration mechanism of the four positional cues—anterior, posterior, dorsal, and ventral—in axolotl limb regeneration

    Sakiya Yamamoto, Saya Furukawa ... Akira Satoh
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Developmental Biology

    SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

    Katharina Uphoff, Melina Hußmann ... Stefan Schulte-Merker
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

    Hyung-Seok Kim, Mary L Sanchez ... Jan L Christian
    Phosphorylation of the BMP4 prodomain is required for proteolytic activation of BMP4 homodimers, but not BMP4/7 heterodimers.