Browse our latest Developmental Biology articles

Boundary cell identity and sharpening of borders are coupled in hindbrain development since both are regulated by mechanical tension.

Genetic analyses combining photoconvertible cell signalling reporters with gain- and loss-of function manipulations reveal a novel role for Notch signalling in controlling Hedgehog response in neural progenitor cells.

Notch signaling controls the collective migration of parapineal cells through its capacity to restrict FGF pathway activation to a few leading cells.

The zebrafish has been established as a genetic and molecular model for the blood-brain barrier.

Cyr61 autoregulating tip cell activity by interlinking integrin and Hippo pathway and targeting Cyr61 provides promising therapeutic approach for the treatment of pathological angiogenesis, including tumour angiogenesis.

Lineage analysis reveals that cardiac neural crest contributes to cardiomyocytes across vertebrates and consistent with this, the neural crest gene regulatory program is reactivated upon heart regeneration in zebrafish.

Sexual differentiation controlled by sex-specific mRNA splicing evolved in a step-wise manner in insects.

Lymphatic-enriched microRNA miR-204 is required for lymphatic development through its effects on the key lymphatic transcription factor NFATC1.

Long-range Ret receptor signaling promotes axon outgrowth and regulates growth cone dynamics in pioneer neurons by inducing transcriptional changes in Myosin-X expression.

The adhesion-GPCR BAI1 shapes dendritic arbors in the hippocampus by associating with Bcr late in development and stimulating its RhoA-GEF activity, resulting in dendritic growth arrest.