Browse our latest Developmental Biology articles

Page 161 of 211
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition

    Miranda Wang, Michael Ly ... Olivia S Rissland
    ME31B is a general repressor of gene expression in the Drosophila early embryo, repressing translation before the maternal-to-zygotic transition and stimulating mRNA decay after activation of the zygotic genome.
    1. Developmental Biology
    2. Neuroscience

    BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities

    Madeline G Andrews, Lorenzo M del Castillo ... Samantha J Butler
    Members of the BMP family of growth factors act as a reiterative code of distinct activities to direct the identities of different classes of sensory neurons in the spinal cord.
    1. Developmental Biology

    Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a

    Vikram Khedgikar, Genevieve Abbruzzese ... Dominique Alfandari
    The regulation of tfap2α expression by adam13 is essential during cranial neural crest cell migration in Xenopus laevis.
    1. Developmental Biology

    Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

    Antonio Galeone, Seung Yeop Han ... Hamed Jafar-Nejad
    N-glycanase 1 is required for a BMP autoregulatory loop in the visceral mesoderm and for intestinal development in Drosophila.
    1. Developmental Biology

    Parallel Activin and BMP signaling coordinates R7/R8 photoreceptor subtype pairing in the stochastic Drosophila retina

    Brent S Wells, Daniela Pistillo ... Claude Desplan
    TGFβ family members instruct a cell fate decision downstream of stochastic signaling in the Drosophila retina to ensure correct pairing between different color photoreceptors for color vision.
    1. Developmental Biology

    A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development

    Christie Ciarlo, Charles K Kaufman ... Leonard I Zon
    Akt activation is required for neural crest differentiation through regulation of Sox10 activity.
    1. Developmental Biology

    Signaling: Enzymatic insights into an inherited genetic disorder

    Liping Zhang, Kelly G Ten Hagen
    Mutations in an enzyme involved in protein degradation affect a signaling pathway that stimulates the development of the digestive tract.
    Version of Record
    Insight
    1. Developmental Biology

    Molecular conservation of marsupial and eutherian placentation and lactation

    Michael W Guernsey, Edward B Chuong ... Julie C Baker
    The short-lived tammar wallaby placenta expresses genes resembling eutherian placentas, establishing marsupials as "placental mammals", further, dynamic lactation allows marsupials to compensate for short placentation by expressing key placental genes in the mammary gland.
    1. Developmental Biology

    Reproduction: What is a placental mammal anyway?

    Patrick Abbot, John A Capra
    Many developmental functions in marsupials and eutherian mammals are accomplished by different tissues, but similar genes.
    Version of Record
    Insight
    1. Computational and Systems Biology
    2. Developmental Biology

    Systems biology derived source-sink mechanism of BMP gradient formation

    Joseph Zinski, Ye Bu ... Mary C Mullins
    Embryo-wide quantitative analysis of BMP signaling in zebrafish embryos, combined with a mathematical model-based computational screen, challenges the prevailing model of an antagonist counter-gradient shaping the gastrula BMP morphogen gradient and supports an antagonist sink with BMP diffusion mechanism.