Browse our latest Developmental Biology articles

Page 180 of 209
    1. Developmental Biology

    Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

    Xinde Zheng, Leah Boyer ... Tony Hunter
    The shutoff of aerobic glycolysis in neuronal differentiation is essential for neuronal survival.
    1. Developmental Biology

    Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism

    Gianpaolo Rando, Chek Kun Tan ... Walter Wahli
    Glucocorticoid receptor directly regulates the transcriptional activity of peroxisome proliferator-activated alpha (PPARα) before birth in anticipation of the sudden shifts in the postnatal nutrient source and metabolic demands.
    1. Cell Biology
    2. Developmental Biology

    The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals

    Tongchao Li, Nikolaos Giagtzoglou ... Hugo J Bellen
    A novel mechanism links two myosins associated with deafness in auditory organs.
    1. Developmental Biology

    Genetic dissection of the Transcription Factor code controlling serial specification of muscle identities in Drosophila

    Laurence Dubois, Jean-Louis Frendo ... Alain Vincent
    Lineage-specific regulatory loops involving evolutionarily conserved myogenic Transcription Factors control muscle identity specification in Drosophila.
    1. Developmental Biology

    Ancient origin of lubricated joints in bony vertebrates

    Amjad Askary, Joanna Smeeton ... J Gage Crump
    Zebrafish have lubricated joints similar to ours and are a tractable model for arthritis research.
    1. Developmental Biology

    Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

    Kenji Kamimoto, Kota Kaneko ... Tohru Itoh
    Clonal tracing in vivo and quantitative modeling in silico reveal a unique mode of tissue growth and structural remodeling of the biliary system, providing an insight into the cellular basis for robust liver regeneration.
    1. Cancer Biology
    2. Developmental Biology

    Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

    Julia Hatzold, Filippo Beleggia ... Matthias Hammerschmidt
    A Na,K-ATPase beta subunit can suppress basal cell carcinogenesis either via its osmoregulatory function to avoid hypotonic stress, or by promoting epithelial polarity and adhesiveness of basal keratinocytes from the overlying outer layer.
    1. Developmental Biology
    2. Plant Biology

    Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy

    Natalie M Clark, Elizabeth Hinde ... Rosangela Sozzani
    The mechanistic basis of molecular movement and interactions within plant root cells can be quantified using scanning fluorescence correlation spectroscopy.
    1. Developmental Biology

    Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration

    Francisco J Barrionuevo, Alicia Hurtado ... Rafael Jiménez
    The vertebrate testis-determining gene, Sox9, also controls adult testis maintenance in mammals, acting redundantly with its paralog Sox8.