Browse our latest Developmental Biology articles

Page 179 of 209
    1. Structural Biology and Molecular Biophysics
    2. Developmental Biology

    Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

    Chase A Weidmann, Chen Qiu ... Aaron C Goldstrohm
    Crystal structures of Nanos bound to Pumilio and target RNAs demonstrate how Nanos forms a molecular clamp to alter Pumilio RNA regulation and specificity in embryonic development and germline maintenance.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos

    Stephen W Eichhorn, Alexander O Subtelny ... David P Bartel
    Profiling of mRNA poly(A)-tail lengths and translational efficiencies provides new insights into posttranscriptional gene regulation in early Drosophila development.
    1. Cell Biology
    2. Developmental Biology

    Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1

    Nicolas J Lehrbach, Gary Ruvkun
    Post-translational processing of the SKN-1A/Nrf1 transcription factor regulates proteasome expression.
    1. Cell Biology
    2. Developmental Biology

    Genetic Screen: Hearing lessons from flies

    Yi-Nan Lee, Cheng-Ting Chien
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Physical association between a novel plasma-membrane structure and centrosome orients cell division

    Takefumi Negishi, Naoyuki Miyazaki ... Naoto Ueno
    A newly discovered membrane structure associates with one of the centrioles and affects two important centrosomal events in epidermal cells – ciliary positioning and spindle orientation – through a physical interaction.
    1. Developmental Biology
    2. Neuroscience

    Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

    Andre Voelzmann, Pilar Okenve-Ramos ... Natalia Sanchez-Soriano
    A novel regulatory cascade downstream of Tau and spectraplakins ensures that synaptic proteins are delivered to axonal terminals in the developing and ageing brain, providing potential explanations for precocious synapse loss in dementias.
    1. Developmental Biology
    2. Plant Biology

    Formation of polarity convergences underlying shoot outgrowths

    Katie Abley, Susanna Sauret-Güeto ... Enrico Coen
    Models that generate tandem alignments of cell polarities are more readily compatible with the formation of PIN1 polarity patterns in plant leaf buds than the most widely accepted “up-the-gradient” model.
    1. Developmental Biology
    2. Plant Biology

    Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer, Denis Janocha ... Jan U Lohmann
    TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.
    1. Developmental Biology
    2. Evolutionary Biology

    Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan

    Isabel Guerreiro, Sandra Gitto ... Denis Duboule
    Despite their extreme morphologies, snakes display a global regulatory strategy of their Hox genes similar to that implemented by mammals with, however, important modifications in enhancer specificity.