Browse our latest Developmental Biology articles

Page 21 of 213
    1. Developmental Biology

    Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration

    Yun Bai, Tyler Harvey ... Chen-Ming Fan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos

    Marius Regin, Yingnan Lei ... Claudia Spits
    Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

    Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen
    Drosophila melanogastereven-skipped enhancers control transcriptional bursting by modulating frequency and amplitude, regardless of varying transcription factor inputs, even when mutated to express in embryonic regions not under selective pressure.
    1. Developmental Biology
    2. Neuroscience

    Dynamic changes in subplate and cortical plate microstructure at the onset of cortical folding in vivo

    Siân Wilson, Daan Christiaens ... Kiho Im
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability

    Ignacy Czajewski, Bijayalaxmi Swain ... Daan MF van Aalten
    Modelling O-GlcNAc transferase intellectual disability reveals the roles of this post-translational modification in regulating normal axonal terminal morphology and maintaining appropriate sleep homeostasis, pharmacological and genetic rescues of O-GlcNAcylation highlight the complexities of addressing this disorder.
    1. Developmental Biology
    2. Neuroscience

    Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

    Denise M Poltavski, Alexander T Cunha ... Takako Makita
    Neural crest and placode lineages both contribute to the enteric nervous system, divergently utilizing Edn3-Ednrb and GDNF-Ret signaling.
    1. Developmental Biology

    Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs

    Shuo Chao, Jun Lu ... Zhao-Jia Ge
    Maternal obesity mouse model reveal that melatonin deficiency causes the genomic hyper-methylation of oocytes via increasing the expression of DNA methyltransferases.
    1. Developmental Biology

    Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad

    Shuhei So, Masayo Asakawa, Hitoshi Sawa
    The mirror-symmetric structure of the Caenorhabditis elegans gonad is established through the Wnt-independent function of a Frizzled protein and three Wnt proteins with distinct roles.
    1. Developmental Biology

    Spinal neural tube formation and tail development in human embryos

    Chloe Santos, Abigail R Marshall ... Andrew J Copp
    Analysis of 108 human embryos aged 3–7 weeks reveals modes of primary and secondary neurulation, regulation of body elongation, somite formation rate, and common occurrence of a split neural tube.
    1. Developmental Biology

    Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

    Alicia Hurtado, Víctor López-Soriano ... Francisco J Barrionuevo
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid