Browse our latest Developmental Biology articles

Pkc53E kinase-mediated downregulation of CSL/Su(H) activity is a direct molecular response to parasitoid wasp infestation in Drosophila, allowing the differentiation of encapsulation-active lamellocytes, thereby ensuring an appropriate immune defense.

Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.

Exposure to ketone bodies in early development can reduce neurological impairments in a strain of the nematode C. elegans with PTEN defects.

PTEN mutations disrupt inhibitory GABAergic signaling, causing neurodevelopmental defects that can be mitigated by β-hydroxybutyrate, which activates DAF-16/FOXO and may offer a therapeutic approach for excitation/inhibition imbalances.

A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.

Cell-cell interaction between neural crest-derived cells and mesoderm-derived cells determine cell fate of mesoderm-derived cell in tongue development through Hh signaling.

Brain ventricular astrogliosis and neuroinflammation precede scoliosis onset in the zebrafish rpgrip1l ciliary mutant and anti-inflammatory treatment drastically reduces scoliosis while correcting urotensin related peptide level is ineffective.

Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.