Browse our latest Developmental Biology articles

Page 29 of 213
    1. Developmental Biology

    Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts

    Yongfeng Luo, Ke Cao ... Wei Shi
    Disrupted mesenchymal Bmpr1a-mediated signaling in fetal mouse lung leads to abnormal airway development and congenital pulmonary cyst formation.
    1. Developmental Biology

    Scaling between cell cycle duration and wing growth is regulated by Fat-Dachsous signaling in Drosophila

    Andrew Liu, Jessica O’Connell ... Richard W Carthew
    Two atypical cadherins regulate organ growth by tuning the coupling of cell cycle duration to organ size.
    1. Developmental Biology

    Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation

    Xianwei Chen, Yanfeng Li ... Zhenguo Wu
    Styxl2, a sarcomeric muscle-specific pseudophosphatase in vertebrates, functions in sarcomere assembly by promoting protein degradation of non-muscle myosin IIs.
    1. Developmental Biology

    SMAD4 promotes somatic-germline contact during murine oocyte growth

    Sofia Granados-Aparici, Qin Yang, Hugh J Clarke
    Depletion of the TGFβ signal-transducer, SMAD4, in granulosa cells of growing follicles reduces the number of filopodia, termed transzonal projections, that stably attach to and mediate communication with the oocyte.
    1. Developmental Biology
    2. Genetics and Genomics

    Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth

    Ruby Oberin, Sigrid Petautschnig ... Patrick S Western
    Growth-delayed offspring generated from eggs that lacked normal epigenetic programming exhibited a remarkable capacity to undergo late gestational fetal growth recovery, despite inefficient placental function.
    1. Developmental Biology

    Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

    Fengzhu Xiong, Andrea R. Tentner ... Sean G. Megason
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells

    Léa Torcq, Sara Majello ... Anne A Schmidt
    Pre-hematopoietic stem cells emerge from the aortic floor according to two radically different morphodynamics whose biomechanics rely on controlling apicobasal polarity in hemogenic precursors, which may impact on their fate.
    1. Developmental Biology

    An important role for triglyceride in regulating spermatogenesis

    Charlotte F Chao, Yanina-Yasmin Pesch ... Elizabeth Rideout
    Triglyceride plays an important role in regulating sperm development.
    1. Developmental Biology
    2. Immunology and Inflammation

    Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

    Tobias Weinberger, Messerer Denise ... Christian Schulz
    In cardiac ischemia/reperfusion injury, resident macrophages orchestrate the immune response and positively influence postinfarct remodeling, whereas recruited macrophages determine infarct size.
    1. Cell Biology
    2. Developmental Biology

    Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

    Corey D Holman, Alexander P Sakers ... Patrick Seale
    Single-cell expression profiling and genetic lineage analysis show that aging impairs adipocyte differentiation from precursor cells and blocks the thermogenic activation of adipocytes during cold exposure.