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An analysis of vestibular projection neurons lacking their motor neuron partners resolves outstanding controversies for whether and how motor neurons shape vestibulo-ocular reflex circuit assembly.

New research shows that the neural circuit responsible for stabilising gaze can develop in the absence of motor neurons, contrary to a long-standing model in the field.

The double helix actin network surrounding the mitochondrial sheath of the sperm midpiece undergoes structural changes prior to the motility cessation during sperm-egg fusion.

Abolishing opposing hair cell orientation in mouse otolith and zebrafish neuromast organs preserves segregation of afferent innervation but affects zebrafish mechanotransduction and mouse vestibular reflexes.

The protein stability of WDR5, the core component of TrxG complex, is controlled by the ubiquitin ligase RNF220, which involves in the maintenance of Hox patterns in mouse hindbrain.

Protein nutritional requirements decrease predictively with mass throughout ontogeny across the animal kingdom.

Pkc53E kinase-mediated downregulation of CSL/Su(H) activity is a direct molecular response to parasitoid wasp infestation in Drosophila, allowing the differentiation of encapsulation-active lamellocytes, thereby ensuring an appropriate immune defense.