Browse our latest Developmental Biology articles

An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.

Greater early developmental growth, as indexed by birth weight, relates to greater cortical volume and area in a stable way through the human lifespan.

Identification of distinct yolk sac-derived macrophage subpopulations in the fetal liver reveals their crucial role in shaping the hematopoietic niche, impacting erythropoiesis and granulopoiesis through direct interactions with long-term hematopoietic stem cells.

Alterations in mTOR signaling drive similar dysregulations in the critical mid-fetal neurodevelopmental processes of neurite outgrowth and cell migration in two distinct subsets of autism, idiopathic and 16p11.2 deletion.

Repulsive guidance cues enhance a dual-functioning axonal trafficking facilitator, allowing navigating axons to ensure proper pathfinding by coordinating positive extension and negative steering during nervous system development.

ROCK and the actomyosin network are essential for multiple aspects of sea urchin skeletogenesis, suggesting an independent deployment of these factors in biomineralization across Eukaryotes.

Cylicin-1, a perinuclear theca protein, is critical for acrosome attachment and sperm head morphology.

This sesquiterpene hormone likely acted as a morphogenesis-to-differentiation switch in archaic embryos before it evolved its postembryonic function as the status quo regulator of insect metamorphosis.

Mouse models reveal fundamental roles of SMAD1/5 in mediating both bone morphogenetic protein signaling pathways and the transcriptional response to progesterone during decidualization.

The transmembrane protein Kit Ligand and the Kit receptor tyrosine kinase are required for synapse function between specific cell types in the mouse cerebellum.