Browse our latest Developmental Biology articles

Many well-studied maternal developmental pathways that are required for embryonic development in Drosophila are regulated by the transcription factor OVO in the Drosophila female germline.

For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.

Experiments on mice show that TMC7, a transmembrane channel-like protein, localizes to the cis-Golgi region in spermatids and that this is essential for acrosome biogenesis and male fertility.

Novel genetic fate-mapping strategies enabled re-analysis of cortical oligodendrocytes derived from dorsal pallium, LGE/CGE, and MGE/POA, challenging the canonical view of substantial LGE/CGE contributions and the elimination of MGE/POA-derived populations.

The contribution of the lateral/caudal ganglionic eminence to the pool of cortical oligodendrocyte precursor cells is minimal.

Genetic mouse models combined with single-cell RNA sequencing reveal the essential role of SRSF2 in directing MyoD progenitors to distinct skeletal muscle domains and controlling their differentiation through the regulation of targeted genes and alternative splicing during skeletal muscle development.

Early moderate consumption of alcohol in pregnancy was sufficient to disrupt the fetal epigenome in newborn mice, and high folate maternal diets had a mitigating effect.

The cellular stress response pathway helps animals evaluate food quality and regulate feeding behavior to adapt in nutrient-deficient environments.

A head concussion model in fruit flies reveals that early-life exposure to mild concussions significantly increases the risk of late-life neurodegeneration, with females especially vulnerable due to reproductive factors.