Browse our latest Developmental Biology articles

The archetypal tumor promoter PMA, which promotes cancer without mutating the DNA, increases Wnt signaling by activating macropinocytosis and membrane trafficking in Xenopus embryos and tumor cells.

A novel in vivo strategy for reversible, multiplexed control of circulating hormone expression levels, achieved by combining genome-editing and intramuscular electroporation of fluorescently tagged hormones in the naturally short-lived turquoise killifish.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

In vitro and in vivo data show that C-natriuretic peptide is significant for increasing mitochondrial bioenergetics by cAMP-PKA pathway and improving cytoplasmic and nuclear maturation of maternally aged oocyte.

Direct mechanical microcantilever-based measurements establish key material parameters describing mechanical response of the early Drosophila embryonic epithelium.

Germline extrachromosomal circular DNAs are mainly formed by microhomology-mediated ligation of nucleosome-protected fragments and barely contribute to de novo genomic deletions at meiotic recombination hotspots.

The absence of DMRT1 induces a male-to-female sex reversal in XY rabbits and complete infertility in both sexes.

Chromatin changes downstream from Drosophila germline stem cells and fertilized zygotes alter how transposable element activity and gene expression are controlled to facilitate differentiation.

Xenopus laevis arose from hybridization of two different frog species millions of years ago, leading to adaptation of the genetic networks controlling early embryonic development and stem cell induction to balance expression between the genes inherited from each ancestor.