Browse our latest Developmental Biology articles

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    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

    Nan Wang, Jing He ... Kehkooi Kee
    The lncRNA landscapes in human germ cells are comprehensively profiled and the functional role of an lncRNA LNC1845 in regulating gene expression of a neighboring coding gene LHX8 is elucidated.
    1. Developmental Biology
    2. Neuroscience

    Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

    Tuo Shi, Marielle O Beaulieu ... David W Raible
    Single-cell transcriptomic analysis defines hair cell and supporting cell types in the zebrafish inner ear, and reveals homologies with cells in the mammalian ear.
    1. Cell Biology
    2. Developmental Biology

    Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development

    Cayla E Jewett, Bailey L McCurdy ... Chad G Pearson
    Trisomy 21, the genetic cause of Down syndrome, produces elevated centrosome protein levels reducing intracellular trafficking to and from the centrosome thereby delaying primary ciliogenesis, ciliary signaling, and mouse cerebellar development.
    1. Cell Biology
    2. Developmental Biology

    Kindlin-2 inhibits TNF/NF-κB-Caspase 8 pathway in hepatocytes to maintain liver development and function

    Huanqing Gao, Yiming Zhong ... Guozhi Xiao
    Biochemical and genetic approaches reveal how the focal adhesion protein kindlin-2 controls the liver development and homeostasis by reducing inflammation.
    1. Cell Biology
    2. Developmental Biology

    Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests

    Clement Karsenty, Celine Guilbeau-Frugier ... Celine Galés
    Eprhin B1 in the cardiomyocyte regulates the maturation of the adult surface crest architecture and of the diastolic function during a late postnatal stage in rodents.
    1. Developmental Biology
    2. Neuroscience

    Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons

    Yasutetsu Kanaoka, Koun Onodera ... Yukako Hattori
    A muscle-derived Wnt signal promotes dendritic branching of somatosensory neurons in response to a concurrent deficiency in vitamins, minerals, and cholesterol.
    1. Developmental Biology
    2. Neuroscience

    Molecular characterization of cell types in the squid Loligo vulgaris

    Jules Duruz, Marta Sprecher ... Simon G Sprecher
    Single-cell transcriptomics correlated with in situ gene expression analysis provide an overview of the diversity and molecular features of cell types in the squid Loligo vulgaris.
    1. Developmental Biology
    2. Genetics and Genomics

    Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology

    Elizabeth A Bearce, Zoe H Irons ... Daniel T Grimes
    Urp1 and Urp2 peptides, expressed in CSF-contacting neurons in the spinal canal, prevent abnormal curvature of the zebrafish spine.
    1. Developmental Biology
    2. Physics of Living Systems

    On the origin of universal cell shape variability in confluent epithelial monolayers

    Souvik Sadhukhan, Saroj Kumar Nandi
    The nearly universal nature of scaled cell shape variability in an epithelial monolayer is unavoidable, irrespective of health or disease, as it comes from a mathematical property.
    1. Developmental Biology
    2. Evolutionary Biology

    Vocal communication is tied to interpersonal arousal coupling in caregiver-infant dyads

    Sam Wass, Emily Phillips ... Louise Goupil
    Infants' vocalisations are contingent on their own stress physiology, and alter the inter-personal dynamics of how stress states are shared across the infant-caregiver dyad.