Browse our latest Developmental Biology articles

Page 52 of 209
    1. Developmental Biology
    2. Evolutionary Biology

    A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint

    Jake Leyhr, Laura Waldmann ... Tatjana Haitina
    Jaw joint regulatory sequence 1 (JRS1) is deeply conserved in most jawed vertebrates and displays a specific enhancer activity in the developing primary jaw joint that contributes to early nkx3.2 gene expression and jaw joint morphology.
    1. Developmental Biology
    2. Neuroscience

    Channel-independent function of UNC-9/Innexin in spatial arrangement of GABAergic synapses in C. elegans

    Ardalan Hendi, Long-Gang Niu ... Kota Mizumoto
    Electrical synapses determine the precise position of chemical synapses in the nervous system.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing

    Wenbo Liu, Xukun Lu ... Jianqiao Liu
    SRSF10 directly binds genes functioning in spermatogonia and regulates their alternative splicing, the defect of which can lead to progenitor expansion failure.
    1. Developmental Biology
    2. Neuroscience

    Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature

    Francesco A Servello, Rute Fernandes ... Javier Apfeld
    C. elegans nematodes can assess faithfully the threat that H2O2 poses by coupling the induction of their H2O2 defenses to the perception of high temperature—an inherent enhancer of the reactivity of H2O2.
    1. Developmental Biology
    2. Neuroscience

    A dynamic and expandable digital 3D-atlas maker for monitoring the temporal changes in tissue growth during hindbrain morphogenesis

    Matthias Blanc, Giovanni Dalmasso ... Cristina Pujades
    The digital 3D-atlas maker will help ascribing neuronal birthdate and neuronal differentiation times upon gene disruption in zebrafish avatars for human diseases, and will allow the integration of the information generated in other laboratories.
    1. Cell Biology
    2. Developmental Biology

    The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation toward the kidney lineage

    Fatma Mansour, Christian Hinze ... Kai M Schmidt-Ott
    CEP83 plays a central role in regulating the development of intermediate mesoderm (IM) nephron progenitors, which may involve direct effects of CEP83 in the nephron progenitor differentiation program and indirect lateral plate mesoderm-mediated effects on the IM.
    1. Developmental Biology

    A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins

    Muntasir Kamal, Levon Tokmakjian ... Peter J Roy
    A meta-analysis yields a spatiotemporal map of gene expression that provides a blueprint for nematode cuticle construction and reveals novel families of cuticular intrinsically disordered proteins.
    1. Developmental Biology

    Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii

    Jennifer McKey, Dilara N Anbarci ... Blanche Capel
    A detailed characterization of mouse ovary development using tissue clearing and 3D lightsheet imaging identifies ovary folding, specification of cortical and medullary domains, and ovary encapsulation as major hallmarks of ovary morphogenesis.
    1. Developmental Biology

    Regulation of Nodal signaling propagation by receptor interactions and positive feedback

    Hannes Preiß, Anna C Kögler ... Patrick Müller
    A subset of the zebrafish Nodal receptor complex is regulated by positive feedback and controls the diffusion and distribution of Nodal signals during germ layer formation.
    1. Developmental Biology
    2. Neuroscience

    Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation

    Emeric Merour, Hatem Hmidan ... Carlos Parras
    A comprehensive analysis of Tensin3 function in oligodendrogenesis links the fields of transcriptional control in oligodendrocyte lineage cells with morphogenetic changes and integrin signaling mediated cell survival.