Browse our latest Developmental Biology articles

A gene causing human variants of sex development and its fly equivalent are required for testicular formation in both species.

Partial ablation of osteocytes alters lineage cell specifications in bone and bone marrow, resulting in the acceleration of skeletal aging.

TRUST, as a rapid and fully automated whole-organ imaging technique, enables high-resolution multicolor 3D imaging at low cost by using a UV-LED for widefield illumination and a color camera while relieving researchers from lengthy and laborious tissue processing protocols.

β-catenin, a key effector of the Wnt signaling pathway, is transported into the nucleus via a direct interaction between its PY-NLS and TNPO1 offering new potential targets for cancer therapeutics.

A newly discovered enhancer region may have allowed vertebrates to evolve the ability to open and close their jaws.

Jaw joint regulatory sequence 1 (JRS1) is deeply conserved in most jawed vertebrates and displays a specific enhancer activity in the developing primary jaw joint that contributes to early nkx3.2 gene expression and jaw joint morphology.

Electrical synapses determine the precise position of chemical synapses in the nervous system.

SRSF10 directly binds genes functioning in spermatogonia and regulates their alternative splicing, the defect of which can lead to progenitor expansion failure.

C. elegans nematodes can assess faithfully the threat that H₂O₂ poses by coupling the induction of their H₂O₂ defenses to the perception of high temperature—an inherent enhancer of the reactivity of H₂O₂.

The digital 3D-atlas maker will help ascribing neuronal birthdate and neuronal differentiation times upon gene disruption in zebrafish avatars for human diseases, and will allow the integration of the information generated in other laboratories.