The NDNF-like factor Nord is a Hedgehog-induced and extracellular-localized dosage-dependent BMP modulator that regulates Drosophila wing patterning and growth.
Ethan Ozment, Arianna N Tamvacakis ... Nagayasu Nakanishi
Developmental genetics of sea anemone mechanosensory neurons provides insights into the deep evolutionary history of mechanoreceptor development in animals.
An induced pluripotent stem-cell-based, human heart and lung co-differentiation model reveals their shared signaling requirement and enables investigation of their developmental mutual interaction and tissue boundary formation.
Zebrafish embryo screen utilizing conserved mechanisms between cancer metastasis and zebrafish gastrulation identifies the HTR2C inhibitor pizotifen as anti-metastasis drugs.
An in-depth map of ATR signaling during mouse meiosis is revealed using a combination of genetic and pharmacological approaches coupled to quantitative mass spectrometry.
The maintenance of diverse cell identities might be coordinated through the interaction between widely acting transcriptional corepressors and cell-specific transcription factors to repress undesired gene expression in a cell-type-specific manner.