Browse our latest Developmental Biology articles

Page 73 of 210
    1. Cell Biology
    2. Developmental Biology

    DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila

    Kristin M Sherrard, Maureen Cetera, Sally Horne-Badovinac
    Stress fibers with multiple adhesions along their lengths and treadmilling dynamics may help migrating epithelial cells maintain a linear trajectory and thereby reinforce their collective motility.
    1. Developmental Biology
    2. Evolutionary Biology

    Biomarkers in a socially exchanged fluid reflect colony maturity, behavior, and distributed metabolism

    Sanja M Hakala, Marie-Pierre Meurville ... Adria C LeBoeuf
    Socially exchanged fluids passed mouth-to-mouth in ant colonies contain protein signatures of colony maturity and individual behavioral role, indicating that this fluid may underlie a distributed metabolism that functions over the scale of the colony.
    1. Developmental Biology
    2. Genetics and Genomics

    Quantitative spatial and temporal assessment of regulatory element activity in zebrafish

    Shipra Bhatia, Dirk Jan Kleinjan ... Wendy A Bickmore
    A new method for quantitative assessment of altered regulatory potential of human enhancers bearing disease-associated mutations using live imaging in zebrafish embryos.
    1. Cell Biology
    2. Developmental Biology

    Correct regionalization of a tissue primordium is essential for coordinated morphogenesis

    Yara E Sánchez-Corrales, Guy B Blanchard, Katja Röper
    During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.
    1. Developmental Biology

    The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling

    Yanyan Ding, Yuzhe Li ... Feng Liu
    A new zebrafish RBC aggregation model is developed to explore the dynamic process and the underlying regulatory mechanisms in blood clot formation.
    1. Developmental Biology
    2. Plant Biology

    Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways

    Jenia Schlegel, Gregoire Denay ... Rüdiger GW Simon
    Plant meristem size and shape is controlled by two intertwined regional feedback signals that are mediated by secreted peptides.
    1. Cell Biology
    2. Developmental Biology

    Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

    Amrutha Kizhedathu, Piyush Chhajed ... Arjun Guha
    Reactive oxygen species can activate the ATR/Chk1 pathway in the absence of detectable DNA damage and without a requirement for DNA damage response proteins.
    1. Cell Biology
    2. Developmental Biology

    Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

    Lianna W Wat, Zahid S Chowdhury ... Elizabeth J Rideout
    Drosophila females store more fat than males because the presence of a functional Transformer protein in females limits adipokinetic hormone production and pathway activity.
    1. Developmental Biology
    2. Neuroscience

    A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation

    Jie Wang, Amir Rattner, Jeremy Nathans
    Using single nucleus RNA sequencing, a complete catalogue of cell types was determined for the mouse iris, and this information was used as a starting point to define the effects of pupil dilation on gene expression and on nuclear morphology.
    1. Cell Biology
    2. Developmental Biology

    Ciliary Hedgehog signaling regulates cell survival to build the facial midline

    Shaun R Abrams, Jeremy F Reiter
    Genetic analysis identifies the origins of midface defects in mouse models of ciliopathies, revealing a role for ciliary Hedgehog signaling in cell survival.