Browse our latest Developmental Biology articles

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    1. Developmental Biology
    2. Evolutionary Biology

    Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity

    Ethan Ozment, Arianna N Tamvacakis ... Nagayasu Nakanishi
    Developmental genetics of sea anemone mechanosensory neurons provides insights into the deep evolutionary history of mechanoreceptor development in animals.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells

    Wai Hoe Ng, Elizabeth K Johnston ... Xi Ren
    An induced pluripotent stem-cell-based, human heart and lung co-differentiation model reveals their shared signaling requirement and enables investigation of their developmental mutual interaction and tissue boundary formation.
    1. Developmental Biology
    2. Neuroscience

    Differential adhesion regulates neurite placement via a retrograde zippering mechanism

    Titas Sengupta, Noelle L Koonce ... Daniel A Colón-Ramos
    Biophysical differential adhesion principles drive non-canonical, zippering mechanisms in vivo, regulating precise neurite placement, and synaptic specificity within Caenorhabditis elegans brain bundles.
    1. Developmental Biology

    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis

    Joji Nakayama, Lora Tan ... Zhiyuan Gong
    Zebrafish embryo screen utilizing conserved mechanisms between cancer metastasis and zebrafish gastrulation identifies the HTR2C inhibitor pizotifen as anti-metastasis drugs.
    1. Developmental Biology
    2. Evolutionary Biology
    Silhoutte of a coqui frog in black on a purple background.

    The Natural History of Model Organisms: The big potential of the small frog Eleutherodactylus coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    The coquí frog is of interest to researchers in fields as diverse as development biology, social behavior and the biology of invasive species.
    1. Developmental Biology

    Tumor Metastasis: Fishing for drugs

    Chinyere Kemet, Emily Hill, Hui Feng
    Screening for drugs that disrupt embryonic development in zebrafish can help identify treatments that suppress metastasis.
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    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Phosphoproteomics of ATR signaling in mouse testes

    Jennie R Sims, Vitor M Faça ... Marcus B Smolka
    An in-depth map of ATR signaling during mouse meiosis is revealed using a combination of genetic and pharmacological approaches coupled to quantitative mass spectrometry.
    1. Developmental Biology
    2. Genetics and Genomics

    The transcriptional corepressor CTBP-1 acts with the SOX family transcription factor EGL-13 to maintain AIA interneuron cell identity in Caenorhabditis elegans

    Josh Saul, Takashi Hirose, H Robert Horvitz
    The maintenance of diverse cell identities might be coordinated through the interaction between widely acting transcriptional corepressors and cell-specific transcription factors to repress undesired gene expression in a cell-type-specific manner.
    1. Developmental Biology

    Regeneration of the larval sea star nervous system by wounding induced respecification to the Sox2 lineage

    Minyan Zheng, Olga Zueva, Veronica F Hinman
    Seastar larvae can regenerate their nervous system by specifying cells to express the gene sox2 to enter neural progenitor states that then follow embryonic gene regulatory modes to form new neurons.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates

    Juliane Glaser, Julian Iranzo ... Deborah Bourc'his
    Zdbf2 is a paternally expressed gene that is mainly expressed in the hypothalamus and promotes appetite and body weight gain in neonates.