Browse our latest Epidemiology and Global Health articles

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    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems

    Asgar H Ansari, Manoj Kumar ... Debojyoti Chakraborty
    The web-server CriSNPr overcomes difficulties associated with the different CRISPR diagnostic platforms that stem from Cas-specific single guide RNA design parameters, thereby minimizing the time and effort required for individual assay design.
    1. Epidemiology and Global Health
    2. Medicine

    Antibody levels following vaccination against SARS-CoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies

    Nathan J Cheetham, Milla Kibble ... Claire J Steves
    Third SARS-CoV-2 vaccination appears to eliminate disparities in anti-Spike antibodies between those who received Pfizer-BioNTech versus Oxford/AstraZeneca for first and second vaccination, but levels remain lower in certain groups such as those on the UK 'Shielded Patient List'.
    1. Epidemiology and Global Health

    The impact of the COVID-19 pandemic on Italian population-based cancer screening activities and test coverage: Results from national cross-sectional repeated surveys in 2020

    Paolo Giorgi Rossi, Giuliano Carrozzi ... Paola Mantellini
    The COVID-19 pandemic caused an important delay in screening activities at the national level and increased the pre-existing individual and geographical inequalities in access.
    1. Epidemiology and Global Health
    2. Medicine

    The impact of lag time to cancer diagnosis and treatment on clinical outcomes prior to the COVID-19 pandemic: A scoping review of systematic reviews and meta-analyses

    Parker Tope, Eliya Farah ... Eduardo L Franco
    Investigating standard lag times prior to the pandemic and identifying key methodological considerations in lag time research can guide future investigations into the impact of time to care for patients with cancer.
    1. Ecology
    2. Epidemiology and Global Health

    Ecology, more than antibiotics consumption, is the major predictor for the global distribution of aminoglycoside-modifying enzymes

    Léa Pradier, Stéphanie Bedhomme
    Mobility across ecological contexts and continents is more important to describe the worldwide spread of bacterial resistance to aminoglycosides (a family of antibiotics), than the consumption of aminoglycosides itself.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

    Emily Martyn, Sarah Eisen ... Philippa C Matthews
    Hepatitis B virus infection is a neglected challenge among communities who are under-served by conventional models of healthcare, requiring enhanced interventions to reduce inequity.
    1. Epidemiology and Global Health

    Participation in the nationwide cervical cancer screening programme in Denmark during the COVID-19 pandemic: An observational study

    Tina Bech Olesen, Henry Jensen ... Berit Andersen
    The participation in cervical cancer screening in Denmark was reduced at the start of the pandemic although with longer follow-up time most women resumed screening.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Future COVID19 surges prediction based on SARS-CoV-2 mutations surveillance

    Fares Z Najar, Evan Linde ... Pratul K Agarwal
    A real-time genomic surveillance approach based on mutation analysis of SARS-CoV-2 proteins has enabled a priori prediction of surge in number of COVID19 infection cases, including those already observed in July and September 2022.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Derivation and external validation of clinical prediction rules identifying children at risk of linear growth faltering

    Sharia M Ahmed, Ben J Brintz ... Daniel T Leung
    Clinical prediction rules could help identify children at risk of slowed growth after an episode of diarrheal illness, and these rules may be generalizable to all children, regardless of diarrhea status.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies

    Richard F Oppong, Antonio Terracciano ... Jun Ding
    Two genome sequencing studies show a consistent association between blood mitochondrial DNA copy number (mtDNAcn) and personality traits and provide support for the hypothesis that mtDNAcn may be a biomarker that connects certain personality characteristics with mortality.