Browse our latest Evolutionary Biology articles

Page 18 of 112
    1. Evolutionary Biology
    2. Neuroscience

    Natural variation in the Caenorhabditis elegans egg-laying circuit modulates an intergenerational fitness trade-off

    Laure Mignerot, Clotilde Gimond ... Christian Braendle
    Caenorhabditis elegans egg-laying behaviour shows pronounced variation in natural populations, making it a promising model to investigate the microevolution of a simple neural circuit.
    1. Evolutionary Biology

    Emergence of catalytic function in prebiotic information-coding polymers

    Alexei V Tkachenko, Sergei Maslov
    Theoretical scenario for prebiotic polymers capable of nonenzymatic replication to acquire an early catalytic function, specifically cleavage activity.
    1. Cell Biology
    2. Evolutionary Biology

    The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals

    Jonathan E Phillips, Duojia Pan
    Genetic analysis of Hippo pathway kinases in a close unicellular relative of animals suggests an ancestral role of this ancient pathway in regulating cytoskeletal dynamics and density of multicellular aggregates.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Caspase-1 activates gasdermin A in non-mammals

    Zachary Paul Billman, Stephen Bela Kovacs ... Edward A Miao
    Amphibians, reptiles, and birds engage pyroptosis using caspase-1 and GSDMA, filling an evolutionary gap in which caspase-1 cleaves GSDME in fish and GSDMD in mammals.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

    Hang Xu, Zihao Yuan ... Li Sun
    Functional divergence of caspase 3 and 7 in vertebrate is mediated by key residue mutation.
    1. Evolutionary Biology
    2. Neuroscience

    Comparative neuroimaging of sex differences in human and mouse brain anatomy

    Elisa Guma, Antoine Beauchamp ... Jason P Lerch
    Comparative neuroimaging quantifies the congruence of regional neuroanatomical sex differences between humans and mice.
    1. Developmental Biology
    2. Evolutionary Biology

    A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis

    Jaaved Mohammed, Neha Arora ... Joanna Wysocka
    SNP-editing of human embryonic stem cells reveals cell type specific function of a genetic variant associated with changes in human jaw shape.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Gene expression plasticity followed by genetic change during colonization in a high-elevation environment

    Huishang She, Yan Hao ... Yanhua Qu
    An integrative approach allows investigations of the relationship between an initial plasticity and the subsequent adaptive evolution during rapid adaptive modification of complex systems in the wild.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

    Florian Bénitière, Anamaria Necsulea, Laurent Duret
    Variation in the rate of alternative splicing across animals are mainly driven by differences in the rate of splicing errors.
    1. Evolutionary Biology

    Oxygen isotopes in orangutan teeth reveal recent and ancient climate variation

    Tanya M Smith, Manish Arora ... Daniel R Green
    A new high-resolution approach to probing tooth chemistry shows real potential to uncover changing rainfall patterns and environmental conditions during human prehistory.