Browse our latest Evolutionary Biology articles

Page 19 of 112
    1. Evolutionary Biology

    Computational Biology: Capturing the unpredictability of stem cells

    Arda Durmaz, Valeria Visconte
    A new mathematical model that can be applied to both single-cell and bulk DNA sequencing data sheds light on the processes governing population dynamics in stem cells.
    Version of Record
    Insight
    1. Evolutionary Biology

    Evolutionary rate covariation is a reliable predictor of co-functional interactions but not necessarily physical interactions

    Jordan Little, Maria Chikina, Nathan L Clark
    Physical interactions are a minor contributor to the correlations in evolutionary rate over time that are observed between co-functional proteins.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Autotrophic growth of Escherichia coli is achieved by a small number of genetic changes

    Roee Ben Nissan, Eliya Milshtein ... Ron Milo
    Achieving autotrophy in E. coli by introducing a small number of genetic changes crosses a milestone in engineering major metabolic transitions and paves a way for sustainable bio-production from CO2.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Epistasis between mutator alleles contributes to germline mutation spectrum variability in laboratory mice

    Thomas A Sasani, Aaron R Quinlan, Kelley Harris
    Germline mutation rates in mice are shaped by two mutator alleles that interact epistatically, showing that DNA repair defects that map to different loci can have snowballing effects.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Tempo and mode of gene expression evolution in the brain across primates

    Katherine Rickelton, Trisha M Zintel ... Courtney C Babbitt
    Larger phylogenetic context is required to understand human and nonhuman primate brain evolution.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    How did UGA codon translation as tryptophan evolve in certain ciliates? A critique of Kachale et al. 2023 Nature

    Estienne Carl Swart, Christiane Emmerich ... Aditi Singh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Genetics and Genomics

    Cell-type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells

    Ban Wang, Alexander L Starr, Hunter B Fraser
    Exploring tissue-specific regulation of gene expression with human-chimpanzee hybrid cells helps us understand how life evolves and what makes us human.
    1. Evolutionary Biology
    2. Plant Biology

    Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

    Lei Zhao, Wei Zhou ... Hong-Tao Li
    Computational analyses, for the first time in plants, reveal how male-biased genes evolve faster than female-biased and unbiased genes.
    1. Structural Biology and Molecular Biophysics
    2. Evolutionary Biology

    Coevolution with toxic prey produces functional trade-offs in sodium channels of predatory snakes

    Robert E. del Carlo, Jessica S. Reimche ... Chris R. Feldman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Evolutionary Biology

    Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator

    Paul Knabl, Alexandra Schauer ... Grigory Genikhovich
    ChIP-seq analysis reveals BMP signaling targets in a cnidarian and identifies ZSWIM4-6 as a dampener of the pSMAD1/5 gradient and a potential conveyor of the BMP-mediated gene repression.