Browse our latest Evolutionary Biology articles

Evolutionary analyses suggest that most mammalian circRNAs did not emerge from common ancestral circRNA precursors, arguing against widespread functional conservation.

Irreversible differentiation into somatic cells is evolutionarily optimal if changing cell phenotype is costly, a few somatic cells already improve the organism's performance, and the organism is large enough.

A new tracking method revealed the social-like interactions in the Mexican blind cavefish, which was thought to be evolutionarily lost, and also demonstrated its mammal-like antagonistic association between the social-like interaction and repetitive behavior.

Human red blood cells from healthy donors display marked biophysical and genetic variation that impacts the growth of Plasmodium falciparum malaria parasites, outside of known disease alleles.

Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.

Graph genotyping of structural variation in diverse human populations reveals functional associations and signatures of local adaptation within poorly resolved regions of the genome.

Quantifying the relationship between census sizes and genetic diversity estimates provides insights into whether natural selection can explain the narrow range of diversity between species.

The relationship between APOE genotype and disease risks may be environmentally moderated, with APOE4 being less harmful and unlikely to increase cardiometabolic risk in a physically active, energy-limited population.

Cas12a CRISPR arrays are sensitive to the GC content of their spacers, but AT-rich separator sequences successfully remove this disruptive effect and enable enhanced multiplexed gene targeting and activation.

Gamete-derived three-amino-acid-loop-extension homeodomain proteins activate zygote development in a strikingly similar manner between basal land plants and green algae, indicating an ancestral role of these transcription factors in green plants.