Browse our latest Evolutionary Biology articles

Page 7 of 119
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Antibody Language Models: Taking the biology seriously makes models better

    Antonio Matas-Gil, Andreas Tiffeau-Mayer
    A new biologically-informed training paradigm enables protein language models to predict affinity maturation trajectories for antibodies.
    Version of Record
    Insight
    1. Neuroscience
    2. Evolutionary Biology

    Three-dimensional and molecular brain atlas of the hagfish reveals the evolutionary origin and early diversification of the vertebrate brain

    Riho Harada, Motoki Tamura ... Daichi G Suzuki
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Ecology
    2. Evolutionary Biology

    Fitness drivers of division of labor in vertebrates

    Irene García-Ruiz, Dustin R Rubenstein
    Direct survival benefits in larger groups rather than kin-selected indirect fitness primarily drive the evolution of division of labor in cooperatively breeding vertebrates, particularly under harsh environmental conditions.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

    Jessica Jocher, Philipp Janssen ... Ines Hellmann
    Analysis of scRNA-seq data from primate embryoid bodies highlights the value of cross-species comparisons for identifying and characterizing cell types, as marker genes can evolve fast.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Separating selection from mutation in antibody language models

    Frederick A Matsen IV, Will Dumm ... Hugh K Haddox
    Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Human genetic ancestry, Mycobacterium tuberculosis diversity, and tuberculosis disease severity in Dar es Salaam, Tanzania

    Michaela Zwyer, Zhi Ming Xu ... Daniela Brites
    The severity of active tuberculosis in a high-burden population is not explained by host or pathogen genetic variation, suggesting a dominant role for social and environmental factors.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Mosaic of somatic mutations in one of Earth’s largest organisms, Pando

    Rozenn M Pineau, Karen E Mock ... Zachariah Gompert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental, regenerative, and behavioral dynamics in acoel reproduction

    Vikram Chandra, Samantha Elizabeth Tseng ... Mansi Srivastava
    Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.
    1. Evolutionary Biology

    Earliest evidence of elephant butchery at Olduvai Gorge (Tanzania) reveals the evolutionary impact of early human megafaunal exploitation

    Manuel Dominguez-Rodrigo, Enrique Baquedano ... Audax Mabulla
    The discovery of the earliest direct evidence of systematic proboscidean butchery at Olduvai Gorge demonstrates that by 1.8 Ma early hominins had strategically integrated megafaunal exploitation into their subsistence systems.
    1. Evolutionary Biology

    No evidence for disassortative mating based on HLA in a small-scale, endogamous population

    Gillian L Meeks, Brooke Scelza ... Brenna M Henn
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling