Browse our latest Genetics and Genomics articles

Regulation of mitochondrial DNA copy number is highly tissue-specific and context-dependent, particularly in the presence of disease.

Phosphorylation of the kinesin-2 motor protein’s elbow region by NEKL-3 kinase maintains autoinhibition, enabling its transport to cilia for sensory function.

Genome-wide epigenetic profiling reveals chromatin regions in the human myometrium involved in functional regulation and hormonal control during pregnancy.

Xist RNA’s influence extends beyond the X-chromosome and its autosomal influence can be perturbed genetically and pharmacologically.

Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.

A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.

A local-ancestry-aware association model identified a suggestive association peak within the HLA class II region linked to TB in a complex, highly admixed Southern African population.

The pro-apoptotic lipid trans-2-hexadecenal impairs mitochondrial protein import and proteostasis by targeting the TOM complex.