Browse our latest Genetics and Genomics articles

A maternal toxin-antidote element has degenerated into an antidote-only remnant in some Caenorhabditis elegans isolates, while in others, the toxin may instead be silenced by small RNAs.

The pathogenicity of MECP2 C-terminal deletions is determined by translational reading frame, enabling prediction of clinical outcome and a shared therapeutic genome editing strategy.

The genomic response of endothelial cells to hypoxia via MOA-seq transcription factor occupancy profiling identified known and novel HIF1A-associated and independent cis-regulatory elements, which defined ten distinct hypoxic kinetic clusters.

DNA-methylation-based predictors of biological age often fail to generalize across human populations, limiting their utility as biomarkers of aging and disease.

A time-dependent genetic interaction between the µ opioid receptor and genes drives early morphine responses in mice, highlighting pathways linked to human substance use disorder.

A single-cell multiomic technique measuring both transcription and chromatin accessibility in the same cell.