Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and revealing new avenues for therapeutic discovery.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Role of ADMA-histones in dual-strand piRNA source loci recognition by Rhino

    Raku Saito, Hirotsugu Ishizu ... Mikiko C Siomi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Cancer Biology

    Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

    Olivia G Waltner, April A Apfelbaum ... Scott N Furlan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Not revised
    Reviewed Preprint v1
    • Inadequate
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Evolutionary Biology
    2. Genetics and Genomics

    The primate Major Histocompatibility Complex as a case study of gene family evolution

    Alyssa Lyn Fortier, Jonathan K Pritchard
    The Major Histocompatibility Complex region evolves via gene birth-and-death, resulting in short-lived genes, rapidly expanding gene subfamilies, and many gene fragments.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Pre-Cambrian origin of envelope-carrying retrotransposons in metazoans

    Shashank Chary, Rippei Hayashi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Joint profiling of cell morphology and gene expression during in vitro neurodevelopment

    Adithi Sundaresh, Dimitri Meistermann ... Helena Kilpinen
    Molecular and morphological profiles of developing neurons in vitro uncover the cellular dynamics of human neurodevelopment and related disease.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Neisseria gonorrhoeae LIN codes: a Robust, Multi-Resolution Lineage Nomenclature

    Anastasia Unitt, Made Krisna ... Odile B Harrison
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells

    Jun Wan, Abby R Thurm ... Lacramioara Bintu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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