Ricardo CH del Rosario, Fenna M Krienen ... Steven A McCarroll
Sibling-derived chimerism in marmosets is found only in cells of hematopoietic origin, especially microglia and macrophages in the brain, whose proportions vary widely across individuals and brain regions.
Stefan Zdraljevic, Laura Walter-McNeill ... Leonid Kruglyak
A maternal toxin-antidote element has degenerated into an antidote-only remnant in some Caenorhabditis elegans isolates, while in others, the toxin may instead be silenced by small RNAs.
The pathogenicity of MECP2 C-terminal deletions is determined by translational reading frame, enabling prediction of clinical outcome and a shared therapeutic genome editing strategy.
The genomic response of endothelial cells to hypoxia via MOA-seq transcription factor occupancy profiling identified known and novel HIF1A-associated and independent cis-regulatory elements, which defined ten distinct hypoxic kinetic clusters.
