Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    The BTB-ZF gene Bm-mamo regulates pigmentation in silkworm caterpillars

    Songyuan Wu, Xiaoling Tong ... Fangyin Dai
    The BTB zinc finger gene Bm-mamo regulates melanin pigmentation in silkworm caterpillars from multiple aspects, including melanin synthesis, pigment granules maturation, and cuticle construction.
    1. Genetics and Genomics
    2. Cancer Biology

    Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

    Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice

    Lauren Kuffler, Daniel A. Skelly ... Gregory W. Carter
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations

    Maria L Adelus, Jiacheng Ding ... Casey E Romanoski
    Primary endothelial cell cultures contain markedly heterogeneous cell subtypes that exhibit distinct molecular responses to disease-relevant exposures.
    1. Developmental Biology
    2. Genetics and Genomics

    Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

    Amandine Jarysta, Abigail L.D. Tadenev ... Basile Tarchini
    1. Developmental Biology
    2. Genetics and Genomics

    Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice

    Hui-Juan Jin, Yong Fan ... Su-Ren Chen
    Cylicin-1, a perinuclear theca protein, is critical for acrosome attachment and sperm head morphology.
    1. Genetics and Genomics

    Expanding the Drosophila toolkit for dual control of gene expression

    Jonathan Zirin, Barbara Jusiak ... Norbert Perrimon
    A CRISPR knock-in approach enables the efficient generation of tissue-specific LexA and QF driver lines which can simultaneously control gene expression in multiple tissues.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Immune Response: Investigating the role of vitamin D in asthma

    Siddhant Sharma, Mayank Garg
    Results in mice suggest that vitamin D reduces the symptoms of asthma by controlling an immune response that leads to inflammation of the airways.
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