Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics
    2. Neuroscience

    Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling

    Jennifer J Tuscher, Angela Cleere ... Jeremy J Day
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

    Vivek Bhardwaj, Alberto Griffa ... Alexander van Oudenaarden
    A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

    Mengyang Shi, Jie Li ... Bin Zhou
    New mouse genetic tools, roxCre and loxCre, facilitate the study of gene function in cells of interest, allowing for simultaneous and efficient gene knockout and precise lineage tracing in vivo.
    1. Genetics and Genomics
    2. Physics of Living Systems

    Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

    Ken-ichiro F Kamei, Koseki J Kobayashi-Kirschvink ... Yuichi Wakamoto
    Conservation levels of gene expression abundance ratios are globally coordinated in cells, and cellular state changes under such biologically relevant stoichiometric constraints are readable as low-dimensional changes in Raman spectra.
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Transposons contribute to splice-isoform diversity in the Drosophila brain

    Malak Choucri, Christoph D Treiber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Ecology

    Plasticity Associated with Adoption of Social Roles in Clown Anemonefish

    Lili F Vizer, Douglas Alvarado ... Peter M Buston
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    The CLAMP GA-binding transcription factor regulates heat stress-induced transcriptional repression

    Joseph Aguilera, Jingyue Duan ... Erica Larschan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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