Browse our latest Genetics and Genomics articles

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    1. Evolutionary Biology
    2. Genetics and Genomics

    Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

    Anna M Langmüller, Jackson Champer ... Philipp W Messer
    1. Developmental Biology
    2. Genetics and Genomics

    Variable paralog expression underlies phenotype variation

    Raisa Bailon-Zambrano, Juliana Sucharov ... James Nichols
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome

    Fabiola García Fernández, Etienne Almayrac ... Emmanuelle Fabre
    A designed system to track homologous recombination (HR) in vivo demonstrates the importance of chromosome organization in the induction of global mobility in response to double-strand breaks and characterizes the role of two types of global motility in HR.
    1. Genetics and Genomics

    Association analyses of host genetics, root-colonizing microbes, and plant phenotypes under different nitrogen conditions in maize

    Michael A Meier, Gen Xu ... Jinliang Yang
    Comprehensive analyses of host genetics, root-associated microbiomes, and plant phenotypes under two nitrogen treatments reveals host genetic control of microbe abundance which, in turn, affects plant performance.
    1. Genetics and Genomics

    Plant Microbiome: How hungry roots get their microbes

    Maggie R Wagner
    Maize genes influence which species of bacteria are recruited from the soil, especially in the absence of nitrogen supplied by fertilizer.
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    1. Genetics and Genomics

    Characterization of full-length CNBP expanded alleles in myotonic dystrophy type 2 patients by Cas9-mediated enrichment and nanopore sequencing

    Massimiliano Alfano, Luca De Antoni ... Marzia Rossato
    A novel sequencing-based method to characterize CNBP microsatellite expansions in DM2 patients demonstrates benefits for an improved dissection of DM2 genetic architecture, thus potentially ameliorating patient stratification and genetic counseling.
    1. Evolutionary Biology
    2. Genetics and Genomics

    GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

    John T Lovell, Avinash Sreedasyam ... Jeremy Schmutz
    GENESPACE lets users track related chromosomal sequences across multiple reference genomes.
    1. Genetics and Genomics

    Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

    Courtney J Smith, Nasa Sinnott-Armstrong ... Jonathan K Pritchard
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Core genes can have higher recombination rates than accessory genes within global microbial populations

    Asher Preska Steinberg, Mingzhi Lin, Edo Kussell
    Homologous recombination rates tend to be highest in the most conserved parts of bacterial genomes.