Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics
    2. Plant Biology

    AT-HOOK-MOTIF NUCLEAR LOCALIZED 15 extends plant longevity by binding at poorly accessible, epigenetic mark-depleted chromatin surrounding transcribed regions

    Thalia Luden, Jihed Chouaref, Remko Offringa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

    Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A Glauser
    Nutritional state dynamically reshapes sensory processing to prioritize behavioral responses, revealing the plastic coupling of sensation, internal state, and behavior.
    1. Genetics and Genomics

    Replicability of Scientific Claims in Drosophila Immunity: A Retrospective Analysis of 400 Publications

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Revised
    Reviewed Preprint v2
    Updated
    • Landmark
    • Convincing
    1. Genetics and Genomics

    A retrospective analysis of 400 publications reveals patterns of irreplicability across an entire life sciences research field

    Joseph Lemaitre, Désirée Popelka ... Bruno Lemaitre
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

    Jack A Bryant, Kara A Staunton ... Manuel Banzhaf
    High-throughput genetics reveals all synthetic-lethal relationships for outer membrane protein biogenesis associated genes in Escherichia coli.
    1. Genetics and Genomics

    A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes

    Alexis G Thornburg, Soo-Young Park ... Marcelo A Nóbrega
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cis-regulation and natural selection in the evolution of human DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Physiology

    NK2R signaling governs intestinal lipid mobilization and mucosal inflammation

    Pedro A Perez, Chung-Chih Liu ... Supriya Srinivasan
    NK2R is a molecular switch linking tachykinin signaling to intestinal lipid handling, mucosal inflammation and gut microbiota, positioning NK2R-targeted peptide therapeutics for cardiometabolic and inflammatory bowel diseases.
    1. Genetics and Genomics

    Dietary Restriction Impacts Peripheral Diurnal Rhythms Important for Longevity in Drosophila

    Dae-Sung Hwangbo, Yong-Jae Kwon ... Ravi Allada
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
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