Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    A retrospective analysis of 400 publications reveals patterns of irreplicability across an entire life sciences research field

    Joseph Lemaitre, Désirée Popelka ... Bruno Lemaitre
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

    Jack A Bryant, Kara A Staunton ... Manuel Banzhaf
    High-throughput genetics reveals all synthetic-lethal relationships for outer membrane protein biogenesis associated genes in Escherichia coli.
    1. Genetics and Genomics

    A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes

    Alexis G Thornburg, Soo-Young Park ... Marcelo A Nóbrega
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cis-regulation and natural selection in the evolution of human DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Revised
    Reviewed Preprint v2
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    • Important
    • Compelling
    • Solid
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Physiology

    NK2R signaling governs intestinal lipid mobilization and mucosal inflammation

    Pedro A Perez, Chung-Chih Liu ... Supriya Srinivasan
    NK2R is a molecular switch linking tachykinin signaling to intestinal lipid handling, mucosal inflammation and gut microbiota, positioning NK2R-targeted peptide therapeutics for cardiometabolic and inflammatory bowel diseases.
    1. Genetics and Genomics

    Dietary Restriction Impacts Peripheral Diurnal Rhythms Important for Longevity in Drosophila

    Dae-Sung Hwangbo, Yong-Jae Kwon ... Ravi Allada
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Transposons contribute to splice-isoform diversity in the Drosophila brain

    Malak Choucri, Tina Rainey, Christoph D Treiber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan
    eLife publishes research on the mechanisms and biological significance of environmentally driven epigenetic inheritance.
    1. Genetics and Genomics
    2. Neuroscience

    Learning is a fundamental source of individuality

    Riddha Manna, Johanni Brea ... Ana Marija Jakšić
    Beyond genotype × environment interactions, which can be shared and identical across individuals, learning from uniquely individual experiences further defines and diversifies individual behaviour.
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