Phosphorylation of the kinesin-2 motor protein’s elbow region by NEKL-3 kinase maintains autoinhibition, enabling its transport to cilia for sensory function.
San Pin Steve Wu, Elvis Quiroz ... Francesco J DeMayo
Genome-wide epigenetic profiling reveals chromatin regions in the human myometrium involved in functional regulation and hormonal control during pregnancy.
Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.
A local-ancestry-aware association model identified a suggestive association peak within the HLA class II region linked to TB in a complex, highly admixed Southern African population.
Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.