Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics
    2. Plant Biology

    Uncovering genetic mechanisms underlying trait variation in switchgrass using explainable artificial intelligence

    Paulo Izquierdo, Xiaoyu Weng ... Shin-Han Shiu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Chromosome-scale genome assembly of the European common cuttlefish Sepia officinalis

    Simone Daniela Rencken, Georgi Tushev ... Gilles Laurent
    A chromosome-scale, annotated reference genome for the common cuttlefish Sepia officinalis clarifies its karyotype and reveals cephalopod-specific gene family expansions across neural and non-neural tissues.
    1. Genetics and Genomics

    A pilot study for whole proteome tagging in C. elegans

    Matthew Eroglu, Oliver Hobert
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle E Sickmann ... Martin Müller
    Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome reorganization and its functional impact during breast cancer progression

    Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

    Paige M Lemen, Yanning Zuo ... Hao Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    The yeast Drosha homolog Rnt1 has a major role in mRNA degradation.
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide composition, G‑quadruplex enrichment, and distinctive nucleosome patterns.
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