Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics
    2. Evolutionary Biology

    Somatic Programmed DNA Elimination is widespread in free-living Rhabditidae nematodes

    Caroline Launay, Eva Wenger ... Marie Delattre
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics
    2. Evolutionary Biology

    Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

    Tom Louis Ducrocq, Damien Laporte, Bertrand Daignan-Fornier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Plant Biology

    Uncovering genetic mechanisms underlying trait variation in switchgrass using explainable artificial intelligence

    Paulo Izquierdo, Xiaoyu Weng ... Shin-Han Shiu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Chromosome-scale genome assembly of the European common cuttlefish Sepia officinalis

    Simone Daniela Rencken, Georgi Tushev ... Gilles Laurent
    A chromosome-scale, annotated reference genome for the common cuttlefish Sepia officinalis clarifies its karyotype and reveals cephalopod-specific gene family expansions across neural and non-neural tissues.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Evolutionary remodeling of non-canonical ORF translation in mammals

    Yue Chang, Tianyu Lei ... Hong Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle E Sickmann ... Martin Müller
    Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome reorganization and its functional impact during breast cancer progression

    Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

    Paige M Lemen, Yanning Zuo ... Hao Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    The yeast Drosha homolog Rnt1 has a major role in mRNA degradation.