Browse our latest Immunology and Inflammation articles

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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    ImmCellTyper facilitates systematic mass cytometry data analysis for deep immune profiling

    Jing Sun, Desmond Choy ... Shahram Kordasti
    ImmCellTyper enhances CyTOF data analysis by combining expert biological knowledge with advanced clustering tools to provide an accurate, comprehensive, and user-friendly solution for high-dimensional immune profiling.
    1. Immunology and Inflammation

    Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components

    Fani Roumelioti, Christos Tzaferis ... George Kollias
    A novel in vivo role for miRNAs Mir221/222 in arthritogenic synovial fibroblasts and progression of arthritis is presented.
    1. Immunology and Inflammation

    Apoptotic caspases cleave DRP1 to promote mitochondrial fusion and anti-viral immune responses

    Yujie Fang, Zihan Guan ... Ke Peng
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

    Youxi Liu, Meimei Yin ... Ling-juan Zhang
    Dermal preadipocytes produce T cell chemokines in response to IFNγ, driving the recruitment and activation of type 1 effector T cells in allergic contact dermatitis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis

    Daniel Spari, Annina Schmid ... Guido Beldi
    Bacteria release ATP as part of their attack in sepsis.
    1. Immunology and Inflammation

    RAG suppresses group 2 innate lymphoid cells

    Aaron M Ver Heul, Madison Mack ... Brian S Kim
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

    Chan-Su Park, Jian Guan ... Scheherazade Sadegh-Nasseri
    Fam49b is a critical regulator of selection process to ensure normal thymocyte development and peripheral T cells survival.