Browse our latest Immunology and Inflammation articles

E3 ligases UBR5 and MARCHF7 restrict SARS-CoV-2 replications through targeting nsp16.

Single-cell and functional analyses uncover distinct immune cell types, revealing specialized functions and deepening insight into invertebrate cellular immunity.

Analysis of monoclonal immunoglobulin A (IgA) antibodies after intranasal immunization highlights the crucial role of secretory IgA in mucosal immunity, enhancing our understanding of how intranasal vaccines can protect against SARS-CoV-2 infection.

Developmental imprinting controls innate type 2 immune function and allergic inflammation.

Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.

During aging, microglia progress through intermediate cellular states, including stress response and translation upregulation states, that modulate subsequent activation and impact cognitive decline.

Functional analyses identify Tfh-like and Tph-like CD4⁺ T cells as drivers of a spontaneous autoimmune syndrome characterized by autoreactive B cells in human immune system mice.

Disruption of RAS–p110α signalling in macrophages impairs both the initiation and resolution of inflammatory responses, revealing a critical regulatory role in immune function and inflammation control.