Browse our latest Immunology and Inflammation articles

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    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

    Matthew C. Pahl, Prabhat Sharma ... Andrew D. Wells
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Exposure to live saprophytic Leptospira before challenge with a pathogenic serovar prevents severe leptospirosis and promotes kidney homeostasis

    Suman Kundu, Advait Shetty, Maria Gomes-Solecki
    1. Immunology and Inflammation

    SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

    Somen K Mistri, Brianna M. Hilton ... Jonathan E. Boyson
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

    Jan Stuchly, David Novak ... Tomas Kalina
    1. Immunology and Inflammation

    Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

    Ziyu Wen, Pingchao Li ... Caijun Sun
    1. Immunology and Inflammation

    Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt

    Phillip A Erice, Xinyan Huang ... Antony Rodriguez
    Mirlet7 functions as a molecular brake of CD8+IL17a+ T cells (Tc17) inflammation and chronic obstructive pulmonary disease via direct regulation RAR-related orphan receptor gamma t (RORγt).
    1. Immunology and Inflammation

    Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

    Xiuyuan Lu, Hiroki Hayashi ... Sho Yamasaki
    Clonotypic tracing of SARS-CoV-2–responsive T cells reveals vaccination-induced dominant Tfh clonotypes, not pre-existing T cells, associated with sustained humoral response, and can serve as an index of antigen-specific antibody longevity.
    1. Immunology and Inflammation

    Development of a new genotype–phenotype linked antibody screening system

    Takashi Watanabe, Hikaru Hata ... Hidehiro Fukuyama
    1. Immunology and Inflammation

    CD81+ fibroblasts, a unique subpopulation with accelerated cellular senescence, exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

    Liangliang Fu, Chenghu Yin ... Haibin Xia
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions

    Pengfei Zhang, Seojin Bang ... Heewook Lee
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