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    1. Medicine
    2. Neuroscience

    Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia

    Naidi Sun, Yu-Yo Sun ... Song Hu
    1. Medicine

    Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

    Megan M Sperry, Berenice Charrez ... Donald E Ingber
    Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue injury.
    1. Medicine

    Nuclear magnetic resonance-based metabolomics with machine learning for predicting progression from prediabetes to diabetes

    Jiang Li, Yuefeng Yu ... Bin Wang
    Lipoprotein particle size and composition, fatty acids, and amino acids were associated with the risk of incident diabetes, and adding the selected metabolites could significantly improve the risk prediction of progression from prediabetes to diabetes beyond the conventional clinical variables.
    1. Chromosomes and Gene Expression
    2. Medicine

    LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling

    Xianghong Xie, Mingyue Gao ... Xiaojun Liu
    1. Medicine
    2. Neuroscience

    Simply crushed Zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice

    Tomohiro Umeda, Ayumi Sakai ... Takami Tomiyama
    1. Medicine
    2. Computational and Systems Biology

    Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

    Hong Yang, Cheng Zhang ... Adil Mardinoglu
    1. Medicine
    2. Neuroscience

    Hemispheric divergence of interoceptive processing across psychiatric disorders

    Emily M Adamic, Adam R Teed ... Sahib S Khalsa
    1. Medicine
    2. Immunology and Inflammation

    Preeclampsia-specific immune cell network in placenta revealed by Cytometry by time of flight and single-cell RNA-seq

    Haiyi Fei, Xiaowen Lu ... Lingling Jiang
    1. Medicine
    2. Cancer Biology

    Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes

    Patrick D Brandt, Dawayne Whittington ... Rebekah L Layton
    1. Medicine

    Point of View: Applied research won’t flourish without basic science

    Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli
    Three senior figures at the US National Institutes of Health explain why the agency remains committed to supporting basic science and research.
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