Browse our latest Medicine articles

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    1. Medicine

    Drug targeting Nsp1-ribosomal complex shows antiviral activity against SARS-CoV-2

    Mohammad Afsar et al.
    Drug targeting Nsp1-ribosome interaction shows rescue of Nsp1-mediated translation inhibition and has antiviral activity against SARS-CoV-2.
    1. Immunology and Inflammation
    2. Medicine

    Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice

    Alex Moshensky et al.
    Chronic, daily inhalation of e-cigarette aerosols alters the inflammatory state of multiple organ systems, including the brain, heart, lung and colon.
    1. Medicine

    Novel protein markers of androgen activity in humans: proteomic study of plasma from young chemically castrated men

    Aleksander Giwercman et al.
    Three new protein markers of testosterone action identified by us, may prove to be valuable as clinical tools in identifying men with testosterone deficiency and in monitoring androgen replacement therapy.
    1. Medicine

    A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines

    Sara Feola et al.
    An immunopeptidomic-based pipeline provides a tool for the identification of cancer therapeutic targets and generation of cancer oncolytic vaccines.
    1. Medicine

    Point of View: Why both sides of the gender equation matter

    Lindy E Barrett
    It is important that any strategy that seeks to move towards gender parity in science and medicine includes actions to address male advantage and overrepresentation as well as female disadvantage and underrepresentation.
    1. Medicine
    2. Microbiology and Infectious Disease
    3. Epidemiology and Global Health
    4. Immunology and Inflammation
    Covid-19. Translational and Clinical Research

    Infectious Diseases: A Collection of Translational and Clinical Research Articles

    Edited by Jos WM van der Meer et al.
    eLife has published articles on a wide range of infectious diseases, including COVID-19, influenza, tuberculosis, HIV/AIDS, malaria and typhoid fever.
    1. Medicine

    Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors

    Alexis Ruiz et al.
    Physiological and biochemical studies show that the treatment of a transgenic mouse model carrying recessive Ryr1 mutations with a combination of class II histone deacetylase inhibitors and DNA methyl transferase inhibitors significantly improves skeletal muscle function.
    1. Cell Biology
    2. Medicine

    Pericyte-mediated constriction of renal capillaries evokes no-reflow and kidney injury following ischaemia

    Felipe Freitas, David Attwell
    Renal capillary pericytes are a novel therapeutic target for reducing sustained reduction in renal blood flow ('no-reflow') after kidney ischaemia.
    1. Computational and Systems Biology
    2. Medicine

    Meta-Research: Author-level data confirm the widening gender gap in publishing rates during COVID-19

    Emil Bargmann Madsen et al.
    The gender gap in publication productivity has increased during the COVID-19 pandemic, with potential implications for the careers of women working in research.
    1. Medicine

    Sulforaphane reduces obesity by reversing leptin resistance

    Işın Çakır et al.
    Sulforaphane through NRF2-dependent and -independent cellular and molecular pathways alleviates leptin resistance to reverse the diet-induced obesity.