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    1. Medicine

    Transparency of research practices in cardiovascular literature

    Gabriel O Heckerman, Eileen Tzng ... Adrienne Mueller
    1. Medicine

    Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans

    Yifan Xiang, Vineeta Tanwar ... Pankaj Kapahi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A Titin Missense Variant Causes Atrial Fibrillation

    Mahmud Arif Pavel, Hanna Chen ... Dawood Darbar
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Medicine

    Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility

    Shahriar Mowla, Linda Farahani ... Channa N Jayasena
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Medicine

    PCBP2 as an intrinsic agi ng factor regulates the senescence of hBMSCs through the ROS-FGF2 signaling axis

    Pengbo Chen, Bo Li ... Xinfeng Zheng
    The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal cells was characterized in vitro.
    1. Medicine

    Three components of glucose dynamics – value, variability, and autocorrelation – are independently associated with coronary plaque vulnerability

    Hikaru Sugimoto, Ken-ichi Hironaka ... Shinya Kuroda
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Medicine

    Time to Eat - A Personalized Circadian Eating Schedule Leads to Weight Loss Without Imposing Calorie Restriction: A Randomized Controlled Pilot Study

    Isabell Wilming, Jana Tuschewski ... Dominic Landgraf
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Medicine

    Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

    Ole Bæk, Tik Muk ... Duc Ninh Nguyen
    Reduced parenteral glucose during neonatal infection redirects hepatic metabolism to oxidative phosphorylation and gluconeogenesis, dampens systemic proinflammatory responses, and significantly enhances survival in preterm newborns.
    1. Medicine
    2. Microbiology and Infectious Disease

    Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection

    Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung'u
    Extremely early antiretroviral therapy during HIV-1 subtype C infection leads to faster decline in genome-intact viruses, reduced genetic complexity, and immune escape, and may enhance reservoir clearance with additional interventional strategies.
    1. Cancer Biology
    2. Medicine

    Development and assessment of a sustainable PhD internship program supporting diverse biomedical career outcomes

    Patrick Brandt, Dawayne Whittington ... Rebekah L Layton
    Internship programs for PhD and postdoctoral trainees are challenging to develop and sustain, but the benefits to interns and other stakeholders are significant and worth the effort and expense.
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