Browse our latest Medicine articles

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    1. Medicine

    Selective androgen receptor degrader (SARD) to overcome antiandrogen resistance in castration-resistant prostate cancer

    Meng Wu, Rongyu Zhang ... Jinming Zhou
    1. Medicine
    2. Microbiology and Infectious Disease

    Sex and prior exposure jointly shape innate immune responses to a live herpesvirus vaccine

    Foo Cheung, Richard Apps ... Jeffrey I Cohen
    In a study of a herpes simplex virus (HSV) vaccine, the combination of sex and prior exposure to the virus resulted in HSV naive women mounting a prominent type I interferon response associated with reduced neutralizing titers to HSV.
    1. Immunology and Inflammation
    2. Medicine

    FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

    Cong Liu, Milena Schönke ... Patrick CN Rensen
    1. Medicine
    2. Neuroscience

    Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

    Peter R Millar, Brian A Gordon ... Beau M Ances
    1. Medicine
    2. Neuroscience

    Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome

    Dongwon Lee, Wu Chen ... Mingshan Xue
    1. Medicine

    Is calcium a link between inflammatory bone resorption and heart disease?

    Gordon L Klein
    A mechanism is proposed that allows investigators to study interventions to delay onset of heart disease in patients suffering from chronic inflammatory disease with bone loss.
    1. Cancer Biology
    2. Medicine

    Procalcitonin for antimicrobial stewardship among cancer patients admitted with COVID-19

    Hiba Dagher, Anne-Marie Chaftari ... Issam Raad
    Procalcitonin could be useful in enhancing antimicrobial stewardship in cancer patients with COVID-19.
    1. Cell Biology
    2. Medicine

    Cellular features of localized microenvironments in human meniscal degeneration: a single-cell transcriptomic study

    Weili Fu, Sijie Chen ... Xuegong Zhang
    A single-cell transcriptome atlas reveals meniscal microenvironment variations during degeneration and cellular heterogeneity foundations of the inner–outer zone differences, suggesting novel cell subtypes as potential therapeutic targets.
    1. Developmental Biology
    2. Medicine

    Meta-Research: The need for more research into reproductive health and disease

    Natalie D Mercuri, Brian J Cox
    An analysis of publications and research grants shows that the volume of research on reproductive organs is much less than that on non-reproductive organs.
    1. Medicine
    2. Physics of Living Systems

    High spatial resolution analysis using automated indentation mapping differentiates biomechanical properties of normal vs. degenerated articular cartilage in mice

    Anand O Masson, Bryce Besler ... Roman J Krawetz
    The method presented here allows researchers to retrieve accurate and reproducible biomechanical properties of mouse cartilage.
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