Browse our latest Medicine articles

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    1. Medicine

    Sperm motility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Paul Fourquin ... Jessica Escoffier
    Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.
    1. Medicine

    Gender differences in submission behavior exacerbate publication disparities in elite journals

    Chaoqun Ni, Isabel Basson ... Vincent Larivière
    Gender differences in submission behavior, driven by self-perceptions of novelty and peer discouragement, limit women’s representation in high-impact journals and, in turn, their scientific visibility and career advancement.
    1. Medicine
    2. Immunology and Inflammation

    A translational transcriptomic signature of vaccine reactogenicity for the evaluation of novel formulations

    Jérémie Becker, Maroussia Roelens ... Laurent Beloeil
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Medicine
    2. Neuroscience

    Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

    Lucas M James, Carlee A Friar ... Benjamin D Philpot
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Medicine
    2. Neuroscience

    Functional Muscle Networks as Biomarkers of Post-Stroke Motor Impairment and Therapeutic Responsiveness

    David O’Reilly, Giorgia Pregnolato ... Giacomo Severini
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Medicine

    The inactivation of DHHC7 in mouse liver promotes diet-induced obesity through a hepatic Prg4–GPR146 axis

    Yingmin Sun, Ying Liu ... Bing Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Medical Imaging: MRI sets its sights on collagen

    Fritz Schick
    Reducing the echo time of a whole-body MRI scanner makes it possible to image collagen, an important structural protein found in bones and tendons.
    Version of Record
    Insight
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    A titin missense variant drives atrial electrical remodeling and is associated with atrial fibrillation

    Mahmud Arif Pavel, Hanna Chen ... Dawood Darbar
    Genetic and electrophysiological studies uncover a mechanism linking a TTN missense variant to atrial fibrillation by coupling titin with potassium channel remodeling, revealing FHL2 as a modulator and therapeutic target.