Browse our latest Medicine articles

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    1. Medicine

    Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

    Wanxia Gai, Ze Zhou ... YM Dennis Lo
    Epigenetic determination of tissue of origin of genetically classified subsets of plasma DNA molecules enhances transplantation monitoring and cancer testing.
    1. Immunology and Inflammation
    2. Medicine

    Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis

    Ada Weinstock, Karishma Rahman ... Edward A Fisher
    Wnt signaling is revealed to be a regulator of macrophage inflammation-resolving state in atherosclerosis through a PGE2-mediated pathway.
    1. Developmental Biology
    2. Medicine

    Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat

    Jingyi Chi, Zeran Lin ... Paul Cohen
    The regulation of sympathetic innervation density by beige adipocytes in subcutaneous fat is important during a critical developmental window, but dispensable during adulthood.
    1. Genetics and Genomics
    2. Medicine

    Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study

    Chiara Fallerini, Sergio Daga ... Elisa Frullanti
    In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.
    1. Genetics and Genomics
    2. Medicine

    COVID-19: Rare variants increase the risk of severe COVID-19

    Frank L van de Veerdonk, Mihai G Netea
    Evidence is mounting that rare loss-of-function variants in the TLR7 gene predispose men with no medical history to severe forms of COVID-19.
    Version of Record
    Insight
    1. Epidemiology and Global Health
    2. Medicine

    Quantifying the impact of quarantine duration on COVID-19 transmission

    Peter Ashcroft, Sonja Lehtinen ... Sebastian Bonhoeffer
    Test-and-release quarantine strategies for traced contacts of confirmed SARS-CoV-2 cases and returning travellers can reduce average quarantine durations while remaining as effective as 10 days of quarantine without testing.
    1. Epidemiology and Global Health
    2. Medicine

    Epidemiological transition to mortality and refracture following an initial fracture

    Thao Phuong Ho-Le, Thach S Tran ... Tuan V Nguyen
    The concept of compound fracture risk is redefined to combine the risk that an individual will sustain a fracture and the risk of mortality once the fracture has occurred.
    1. Medicine
    2. Neuroscience

    Citizen Science: Asking questions of psychedelic microdosing

    Lindsay P Cameron
    A citizen science approach to research has shown that the improvements in mood and cognition associated with psychedelic microdosing are likely due to a placebo effect.
    Version of Record
    Insight
    1. Medicine
    2. Neuroscience

    Self-blinding citizen science to explore psychedelic microdosing

    Balázs Szigeti, Laura Kartner ... David Erritzoe
    The anecdotally reported benefits of psychedelics microdosing can be explained by the placebo effect.
    1. Epidemiology and Global Health
    2. Medicine

    Osteoporotic Fracture: Bone age is not just for kids

    Jane A Cauley, Dolores M Shoback
    More informed discussions between physicians and older adults about the consequences of an initial osteoporotic fracture could encourage more patients to consider treatments that protect against future fracture.
    Version of Record
    Insight