Browse our latest Microbiology and Infectious Disease articles

Page 113 of 165
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

    Nir Drayman, Parthiv Patel ... Savaş Tay
    Single-cell analyses of cells infected by Herpes Simplex Virus 1 revealed extreme heterogeneity among infected cells, including the robust activation of developmental gene programs in highly infected cells.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

    Nancy L Meyer, Guiqing Hu ... Michael Stewart Chapman
    Cryo-electron microscopy reveals interactions at the interface between adeno-associated virus and its cellular receptor at 2.4Å resolution.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

    Leah Guthrie, Sarah Wolfson, Libusha Kelly
    A network of the gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs and supports the generation of mechanistic hypotheses of microbiome metabolic phenotypes that shape human biology.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly

    Snježana Mikuličić, Jérôme Finke ... Luise Florin
    ADAM17 is a key player in the non-canonical endocytosis pathway that is used by oncogenic papillomaviruses as it allows virus/receptor platform assembly by activation of the ERK1/2 signaling pathway.
    1. Microbiology and Infectious Disease

    Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2

    Andrew Tze Fui Liew, Yong Hwee Foo ... Linda J Kenney
    Inside the acidic vacuole, expression, DNA binding and DNA binding affinity of the Salmonella regulator SsrB is stimulated by acid pH.
    1. Microbiology and Infectious Disease

    Evolution: ANP32B, or not to be, that is the question for influenza virus

    Steven F Baker, Andrew Mehle
    The evolutionary history of ANP32 proteins impacts how the influenza virus jumps from birds to mammals.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Species specific differences in use of ANP32 proteins by influenza A virus

    Jason S Long, Alewo Idoko-Akoh ... Wendy Barclay
    Chicken ANP32A, and not chicken ANP32B, supports influenza polymerase activity and thus editing of this single gene may generate chickens that are resilient to influenza virus infection.
    1. Microbiology and Infectious Disease

    The Plasmodium liver-specific protein 2 (LISP2) is an early marker of liver stage development

    Devendra Kumar Gupta, Laurent Dembele ... Thierry Tidiane Diagana
    LISP2 expression marks the beginning of awakening of dormant hypnozoite to developing malaria liver stages, which are susceptible to a novel prophylactic drug, Plasmodium PI4K inhibitor.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Influenza A virus surface proteins are organized to help penetrate host mucus

    Michael D Vahey, Daniel A Fletcher
    By distributing receptor-binding and receptor-destroying proteins asymmetrically on their surface, filamentous influenza A virus particles create a Brownian ratchet that facilitates their passage through mucus.
    1. Microbiology and Infectious Disease

    RETRACTED: Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer

    Yang Li, Kai-Xuan Li ... Jie Yan
    L. interrogans utilizes endocytic recycling and vesicular transport systems for transcytosis across endothelial or epithelial barrier in blood vessels or renal tubules, which contributes to spreading and transmission of leptospirosis.