Browse our latest Microbiology and Infectious Disease articles

Page 113 of 169
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

    Nimisha Chaturvedi, Evguenia S Svarovskaia ... Jacques Fellay
    Integrated analysis of IFN-λ and HCV amino acid variation indicates the key role of host innate immunity in viral control.
    1. Ecology
    2. Microbiology and Infectious Disease

    Endangered wild salmon infected by newly discovered viruses

    Gideon J Mordecai, Kristina M Miller ... Curtis A Suttle
    Newly discovered viruses in dead and dying farmed Chinook salmon are widely distributed in threatened wild Chinook and sockeye salmon populations.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Pressure-driven release of viral genome into a host nucleus is a mechanism leading to herpes infection

    Alberto Brandariz-Nuñez, Ting Liu ... Alex Evilevitch
    Internal DNA pressure of tens of atmospheres inside a herpesvirus capsid powers ejection of the viral genome into a cell nucleus, causing infection.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin

    Juhye M Lee, Rachel Eguia ... Jesse D Bloom
    Single viral mutations can escape polyclonal human immunity to influenza hemagglutinin, but different mutations escape the immunity of different people.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Subtle selectivity in a pheromone sensor triumvirate desynchronizes competence and predation in a human gut commensal

    Johann Mignolet, Guillaume Cerckel ... Pascal Hols
    A new cell–cell communication system in Streptococcus salivarius, a human gut commensal, discriminates between close signaling molecules to specifically produce bacteriocin-based antimicrobials and disconnects it from foreign DNA acquisition.
    1. Microbiology and Infectious Disease

    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

    Ting Pan, Zheng Song ... Hui Zhang
    USP49 can increase A3G protein expression and enhance its anti-HIV-1 activity, which is also correlated with hypermutations and affects the HIV-1 latent reservoir.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

    Lu Yu, Valerie P O'Brien ... Thomas J Hannan
    Polarizing susceptibilities to recurrent bladder infection are shaped by a duality in TNFɑ-mediated inflammation dynamics upon challenge infection that is dictated by the outcome of the initial infection.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites

    Peter Major, Kacper M Sendra ... Robert P Hirt
    Transporters shared by fungal intracellular parasites provide new insights into the evolution of nucleotide and energy parasitism.
    1. Microbiology and Infectious Disease

    Nanoscale organization of rotavirus replication machineries

    Yasel Garcés Suárez, Jose L Martínez ... Carlos F Arias
    Super-resolution microscopy reveals, at nanometric-scale, the highly organized protein structure of viroplasms, the viral factories used by rotavirus to replicate its genome and assemble new viral particles.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Formin-2 drives polymerisation of actin filaments enabling segregation of apicoplasts and cytokinesis in Plasmodium falciparum

    Johannes Felix Stortz, Mario Del Rosario ... Sujaan Das
    Formin-2 controls spatiotemporal polymerisation of actin filaments, a common mechanism used by apicomplexans for effective segregation of essential chloroplast-like organelles called apicoplasts, and additionally for daughter formation in Plasmodium falciparum.