Browse our latest Microbiology and Infectious Disease articles

Page 113 of 167
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway

    Samantha Del Borrello, Margot Lautens ... Andrew G Fraser
    Parasitic helminths infect over a billion humans and use unusual anaerobic metabolism that needs a rare electron carrier, Rhodoquinone (RQ), whose synthesis requires the kynurenine pathway of tryptophan degradation.
    1. Microbiology and Infectious Disease

    The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

    D Garrett Brown, Raymond Soto ... June L Round
    Immune stimulation from the microbiota prevents neurological damage associated with viral infection of the central nervous system.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structure of the Helicobacter pylori Cag type IV secretion system

    Jeong Min Chung, Michael J Sheedlo ... Melanie D Ohi
    The Helicobacter pylori Cag T4SS has unique structural features, including unexpected symmetry mismatch between sub-complexes, with implications for protein secretion.
    1. Microbiology and Infectious Disease

    Heterogeneity in surface sensing suggests a division of labor in Pseudomonas aeruginosa populations

    Catherine R Armbruster, Calvin K Lee ... Matthew R Parsek
    Subpopulations of polysaccharide producer and surface explorer cells play specialized roles in early Pseudomonas aeruginosa biofilm formation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides

    Mattia Ficarelli, Harry Wilson ... Chad M Swanson
    KHNYN, a putative endoribonuclease, interacts with the zinc-finger antiviral protein (ZAP) and is required for the inhibition of HIV replication and RNA abundance by CpG dinucleotides.
    1. Microbiology and Infectious Disease

    A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation

    Soo-Kyoung Kim, Justin D Lormand ... Vincent T Lee
    RNA degradation is completed through specific intermediates, such as diribonucleotides, which must be removed from the cells by a specific enzyme.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

    Eduardo A Bignon, Amelina Albornoz ... Nicole D Tischler
    Hantavirus spikes are related laterally by 2-fold Gc contacts that can be disulfide-linked and display a temperature-dependent dynamic behavior at neutral pH, exposing and masking the Gc fusion loops.
    1. Microbiology and Infectious Disease

    Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA

    Tera C Levin, Brian P Goldspiel, Harmit S Malik
    Legionella pneumophila can be inhibited by its own antimicrobial, HGA (homogentisic acid), but its density-dependent resistance to HGA restricts the potential for self-harm.
    1. Microbiology and Infectious Disease

    Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

    MengJie Hu, Keith E Schulze ... David A Jans
    RSV's unique ability to co-opt host cell mitochondria to facilitate viral infection reveals the RSV-mitochondrial interface as a viable target for therapeutic intervention.
    1. Microbiology and Infectious Disease

    Bacteria: How Legionella defend their turf

    Elisa D Hughes, Michele S Swanson
    Communities of bacteria that cause Legionnaire’s disease repel other bacteria by secreting an acid called HGA.
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