Browse our latest Microbiology and Infectious Disease articles

NSF is part of a membrane trafficking quality control system that disassembles both properly formed and off-pathway SNARE complexes, and the disassembly activity may be regulated by complexin.

Temperature and ionic conditions control the mechanical properties of virally encapsidated DNA and act as a switch between synchronized and desynchronized genome ejection dynamics in a phage population.

Distinct antiviral signaling pathways, triggered by the aryl hydrocarbon receptor and Interferon-gamma, converge on CDK/cyclin repression, causing inhibition of viral DNA synthesis.

Considerable differences are observed in the global dissemination patterns of HBV-D and HBV-A, the genotypes of which have putative origins in North Africa/Middle East (HBV-D) and the Middle East/Central Asia (HBV-A).

Comprehensive investigation reveals the variability and importance of the nuclear pore complex in HIV-1 infection and the activity of the antiretroviral protein, MX2.

Engagement of both host and parasite signaling pathways proves a novel approach for developing improved anti-parasitic therapies.

Development of a generally adaptable conformational capture assay for use in-trans identifies the specific direct interaction sites between the parvovirus minute virus of mice and the cellular genome during infection as sites of cellular DNA damage.

The packaging signal in HIV-1 genomic RNA supports in vitro particle assembly more efficiently than control RNAs, probably explaining its selective packaging during virus assembly in vivo.

A combination of surveillance data, paired sera and mathematical modelling reveals which factors may influence dengue transmission and control in island settings.

Cryo-EM and X-ray structures of α-xenorhabdolysin in soluble and pore form of Xenorhabdus nematophila give novel insights into the mechanism of action of bi-component α-pore-forming toxins.