Browse our latest Microbiology and Infectious Disease articles

While HIV-1 Gag protein binds tightly to several RNAs, it binds to the viral RNA 'packaging signal' with higher specificity than to control RNAs.

The identification of horizontally transferred genes, and commonly transferred functions, can provide a window into the selective forces acting on species within an ecosystem.

Cryo-electron tomography unveils striking new structural components of positive-strand virus RNA replication compartments, greatly advancing mechanistic insights into the structure, assembly, function and control of these critical complexes.

Plant viruses enhance their replication in vector insects by activating the vector's JNK pathway, and inhibition of this pathway may be a useful strategy for controlling transmission of plant viruses.

A new assay for specific mutational classes provides preciseestimates of the mutation rates and mutational bias for influenza A viruses.

The influenza virus mutates faster than we previously thought.

Microfluidic-based mini-metagenomics enables the investigation of environmental microbial communities in high-throughput and with single-cell resolution, facilitating genome binning and quantification of function, abundance, and genome variation.

Common kidney disease risk variants in African populations are associated with reduced susceptibility to deadly African trypanosomes.

PI(4,5)P2 plays a much broader role during the HIV-1 particle assembly process than assumed; it is indispensable not only for recruitment of Gag to the plasma membrane but also for the maintenance of Gag assemblies.

Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.