Browse our latest Microbiology and Infectious Disease articles

Page 18 of 166
    1. Microbiology and Infectious Disease

    Gut Microbes: Regulating uric acid

    Caihong Hu
    Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Exposure to live saprophytic Leptospira before challenge with a pathogenic serovar prevents severe leptospirosis and promotes kidney homeostasis

    Suman Kundu, Advait Shetty, Maria Gomes-Solecki
    Potential commensalism between saprophytic and pathogenic Leptospira within a vertebrate host protects against severe leptospirosis and improves kidney homeostasis which helps Leptospira interrogans complete its enzootic cycle.
    1. Microbiology and Infectious Disease

    A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor

    Brenna Walton, Serena Abbondante ... Arne Rietsch
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Heparan sulphate binding controls in vivo half-life of the HpARI protein family

    Florent Colomb, Abhishek Jamwal ... Henry J McSorley
    The HpARI family members can either suppress or amplify responses to IL-33, and also differ in their half-life in vivo due to binding to the extracellular matrix constituent, heparan sulphate.
    1. Microbiology and Infectious Disease

    Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides

    Yang Fu, Xiao-Dan Luo ... Wence Wang
    Lactobacillus plantarum regulates host uric acid metabolism via its own nucleoside hydrolase iunH.
    1. Microbiology and Infectious Disease

    Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

    Sasmita Panda, Yahani P Jayasinghe ... Vinai C Thomas
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Microbiology and Infectious Disease

    Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth

    Lianhua Qin, Junfang Xu ... Haipeng Liu
    Galectin-9 directly binds to arabinogalactan (AG), leading to the identification of AG-specific monoclonal antibodies that effectively inhibit Mycobacterium tuberculosis growth, providing insights for novel tuberculosis therapies.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM

    Lina Antenucci, Salla Virtanen ... Perttu Permi
    Robust NMR approach allowed simultaneous detection of substrate cleavage site and real-time kinetics of hydrolysis for Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM, and revealed D-alanyl-glycine activity for LytM.
    1. Microbiology and Infectious Disease

    RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses

    Bill Kwan-wai Chan, Yingxue Li ... Sheng Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

    Hoang Thanh Hai, Le Thanh Hoang Nhat ... Nguyen Thuy Thuong Thuong
    An unbiased transcriptomic analysis enhances understanding of inflammatory pathways and genes linked to TBM pathogenesis and mortality, identifying potential markers for poor prognosis or therapeutic targets.