Browse our latest Microbiology and Infectious Disease articles

Page 17 of 175
    1. Microbiology and Infectious Disease

    Stumpy forms are the predominant transmissible forms of Trypanosoma brucei

    Jean Marc Tsagmo Ngoune, Parul Sharma ... Brice Rotureau
    According to experimental and field observations, stumpy forms appear to be the most adapted forms for African trypanosome transmission from the mammalian host to the tsetse fly in natural conditions.
    1. Microbiology and Infectious Disease

    Caffeic acid phenethyl ester protects Clostridioides difficile infection by toxin inhibition and microbiota modulation

    Yan Guo, Yong Zhang ... Jiazhang Qiu
    Caffeic acid phenethyl ester treats Clostridioides difficile infection by neutralizing Clostridioides difficile toxin B and altering the gut microbiota and metabolites.
    1. Microbiology and Infectious Disease

    A within-host infection model to explore tolerance and resistance

    David Duneau, Pierre DM Lafont ... Jean-Baptiste Ferdy
    A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of current experimental proxies and proposing new methods to better understand host resistance and disease tolerance.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A general mechanism for initiating the bacterial general stress response

    Rishika Baral, Kristin Ho ... Niels Bradshaw
    A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable toolkit for bacterial signaling.
    1. Microbiology and Infectious Disease

    Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence

    John A Buglino, Yaprak Ozakman ... Michael S Glickman
    M. tuberculosis produces a copper binding diisonitrile chalkophore to maintain the copper-dependent respiratory oxidase during infection, identifying a pathogen strategy that defends oxidative phosphorylation against host attack.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Cell Surface Receptors: Virus attacks fish by muscling its way into cells

    Ping-Ping Liu, Zhe Wei, Xian-Wei Wang
    Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.
    Version of Record
    Insight
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structure of an oxygen-induced tubular nanocompartment in Pyrococcus furiosus

    Wenfei Song, Jan Fiala ... Friedrich Förster
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease

    Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA

    Aleksandr Korotaev, Quirin Niggli ... Christoph Dehio
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A suite of selective pressures supports the maintenance of alleles of a Drosophila immune peptide

    Sarah R Mullinax, Andrea M Darby ... Robert L Unckless
    Genetic variation in an immune peptide is maintained by multiple selective forces including an interplay between systemic immunity, sex, and the microbiome.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Synonymous mutations in AAV Rep enhance genome packaging in a library selection

    Tasfia Azim, Dru Myerscough, Jonathan J Silberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete