Browse our latest Microbiology and Infectious Disease articles

The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

Routine genomic surveillance uncovered a decades-long multidrug-resistant Pseudomonas aeruginosa outbreak sustained by patient reservoirs and hospital plumbing, enabling targeted infection control measures that ultimately curtailed transmission.

Intermolecular steric repulsion generated by glycans on the cell membrane inhibits viral infection by preventing the formation of a virus-cell interface, regardless of the identity of molecules for glycan modification.

Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.

The pneumococcal capsular serotype and genetic background, as well as a combination of genomic loci, influence intrinsic pneumococcal growth kinetics, which may have implications for pneumococcal disease pathogenesis.

High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.

Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.

Drug repurposing screens reveal several epigenetic inhibitors as active against P. vivax hypnozoites demonstrating that epigenetic pathways play a central role in hypnozoite quiescence.

A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain environments.