Browse our latest Microbiology and Infectious Disease articles

Page 17 of 178
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Dissecting organoid-bacteria interaction highlights decreased contractile force as a key factor for heart infection

    Anheng Wang, Jiaxian Wang ... Chunming Wang
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis

    Junghoon Lee, Scot P Ouellette
    For the first time, a function for the second messenger molecule, cyclic di-AMP, in Chlamydia has been described, revealing its role in regulating chlamydial developmental cycle progression.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity

    Khund Sayeed, Sreeja Parameswaran ... Matthew T Weirauch
    Infection of human cells by human cytomegalovirus induces massive changes to human chromatin and reduction of TEAD1 activity.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development

    Pramila Rijal, Leiyan Wei ... Alain RM Townsend
    Grafting surface loops containing antibody epitopes of a poorly expressed flu neuraminidase protein onto a high-expressing, stable scaffold improves its production and stability for vaccine development.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The Mycobacterium tuberculosis complex pangenome is small and shaped by sub-lineage-specific regions of difference

    Mahboobeh Behruznia, Maximillian Marin ... Conor J Meehan
    The accessory genome of Mycobacterium tuberculosis is small, but differences in gene content are found both between and within lineages.
    1. Microbiology and Infectious Disease

    Spatial integration of sensory input and motor output in Pseudomonas aeruginosa chemotaxis through colocalized distribution

    Zhengyu Wu, Maojin Tian ... Junhua Yuan
    In Pseudomonas aeruginosa, the chemoreceptor cluster and flagellar motor colocalize at the same cell pole through FlhF anchoring, preventing cross-pathway signaling interference between chemotaxis and c-di-GMP regulation.
    1. Microbiology and Infectious Disease

    Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression

    Xu Liu, Yuchen Xie ... Jing Li
    Gut dysbiosis and specific microbiota composition promoted the absorption of excess palmitic acid in the ileum, driving its accumulation in the serum.
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling in human papillomavirus type 16-infected cervical cancer cells

    Haibin Liu, Lulu Yu ... Zhi-Ming Zheng
    A newly discovered long noncoding RNA lnc-FANCI-2 suppresses RAS signaling to modulate Akt and Erk1/2 phosphorylation in high-risk HPV cervical cancer, consequently regulating HPV carcinogenesis.
    1. Microbiology and Infectious Disease

    Temporal dynamics of viral fitness and the adaptive immune response in HCV infection

    Melanie Rose Walker, Preston Leung ... Rowena A Bull
    Early immune pressure and co-occurring mutations drive changes in hepatitis C virus fitness and evolution, revealing key dynamics in the establishment of chronic infection.
    1. Microbiology and Infectious Disease

    A novel mechanism for bacterial sporulation based on programmed peptidoglycan degradation

    Carlos A Ramírez Carbó, Oihane Irazoki ... Beiyan Nan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid