Browse our latest Microbiology and Infectious Disease articles

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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Synchronization of oscillatory growth prepares fungal hyphae for fusion

    Valentin Wernet, Marius Kriegler ... Reinhard Fischer
    Fungal hyphae constantly undergo signal oscillations, comparable to a cell 'monologue' until they meet another hypha with which they then coordinate signal oscillations and transit into a cell-to-cell dialogue.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A CRISPR-based rapid DNA repositioning strategy and the early intranuclear life of HSV-1

    Juan Xiang, Chaoyang Fan ... Pei Xu
    An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A pH-sensitive switch activates virulence in Salmonella

    Dasvit Shetty, Linda J Kenney
    A single conserved residue – histidine 12 – confers pH-sensitive DNA binding to the Salmonella Typhimurium SPI-2 transcriptional regulator SsrB, thereby regulating Salmonella virulence.
    1. Microbiology and Infectious Disease

    Evolution of a functionally intact but antigenically distinct DENV fusion loop

    Rita M Meganck, Deanna Zhu ... Longping V Tse
    Operating as a serum profiling tool for dengue infection and vaccination, the D2-FLM variant, which is insensitive to antibody-dependent enhancement-prone fusion loop antibodies, also offers potential for a safer dengue virus vaccine.
    Version of Record
    Short Report
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    1. Microbiology and Infectious Disease

    Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis

    Somnath Shee, Reshma T Veetil ... Amit Singh
    Genome-scale integration of transposon mutagenesis with a redox biosensor identified a hypothetical transcription factor- Rv0158 required to calibrate the growth, cytoplasmic redox potential, and respiration of Mycobacterium tuberculosis in response to metabolic switching from glucose to fatty acids.
    1. Microbiology and Infectious Disease

    C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants

    Pamela Ferretti, Jakob Wirbel ... Peer Bork
    Not revised
    Reviewed Preprint v1
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

    Megan E Carey, Zoe A Dyson ... Global Typhoid Genomics Consortium Group Authorship
    An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Influenza virus transcription and progeny production are poorly correlated in single cells

    David J Bacsik, Bernadeta Dadonaite ... Jesse D Bloom
    Quantification of both viral transcription and progeny production from single influenza-infected cells shows that the cells that produce the most viral RNA often do not produce the most virions.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    COVID-19 and Cancer: Acting on past lessons and learning new ones

    Eduardo L Franco, Diane M Harper
    eLife has published a special issue containing articles that examine how cancer prevention, control, care and survivorship were impacted by the COVID-19 pandemic.
    1. Medicine
    2. Microbiology and Infectious Disease

    The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2

    Hsiao-Fan Chen, Wei-Jan Wang ... Mien-Chie Hung
    Two natural tannins, oligomeric proanthocyanidins and punicalagin, acted as potent inhibitors against SARS-CoV-2 infection, and grape seed extract supplementation could serve as a healthy food for infection prevention.