Browse our latest Neuroscience articles

Page 17 of 623
    1. Neuroscience

    Hierarchical Bayesian modeling of multiregion brain cell count data

    Sydney Dimmock, Benjamin MS Exley ... Cian O'Donnell
    Bayesian hierarchical models offer powerful statistical tools for neuroscientists to analyze whole-brain cell count data, as demonstrated here using two example datasets from different laboratories.
    1. Neuroscience

    Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the Drosophila neuromuscular junction

    Yen-Ching Chang, Yi-Jheng Peng ... Karen T Chang
    Peripheral glia regulate synaptic remodeling at the Drosophila neuromuscular junction by balancing neuron-derived signals and controlling ambient glutamate levels, thereby revealing distinct glial mechanisms in activity-dependent synaptic plasticity.
    1. Neuroscience

    PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features

    Min Zhang, Naoto Kubota ... Sika Zheng
    PTBP1 loss in mature astrocytes causes unique astrocytic splicing changes, not neuronal-like, contrasting its role in other non-neuronal cells and indicating PTBP1 depletion alone is ineffective to drive adult-astrocyte-to-neuron conversion.
    1. Neuroscience

    Progressive remote memory decline coincides with parvalbumin interneuron hyperexcitability and enhanced inhibition of cortical engram cells in a mouse model of Alzheimer’s disease

    Julia J van Adrichem, Rolinka J van der Loo ... Ronald E van Kesteren
    Remote memories in Alzheimer’s disease are impaired through loss of inhibitory control over cortical engram neurons by hyperexcitable parvalbumin interneurons.
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katherine X Dong, Hui Ji ... Colleen N McLaughlin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Spatially heterogeneous inhibition projects sequential activity onto unique neural subspaces

    Andrew B Lehr, Arvind Kumar, Christian Tetzlaff
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Synaptic density and relative connectivity conservation maintain circuit stability across development

    Ingo Fritz, Feiyu Wang ... André Ferreira Castro
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Reconstructing Voice Identity from Noninvasive Auditory Cortex Recordings

    Charly Lamothe, Etienne Thoret ... Pascal Belin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A stochastic RNA editing process targets a select number of sites in individual Drosophila glutamatergic motoneurons

    Andrés B Crane, Michiko O Inouye ... J Troy Littleton
    Patch-seq RNA profiling defines the overall RNA editing landscape and single neuron editing rules for individual genetically defined Drosophila larval motoneurons.
    1. Neuroscience

    Cholecystokinin modulates age-dependent thalamocortical neuroplasticity

    Xiao Li, Jingyu Feng ... Jufang He
    Cholecystokinin gates age-dependent auditory thalamocortical plasticity and, upon supplementation, reverses age-related plasticity decline and improves frequency discrimination.