Browse our latest Neuroscience articles

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    1. Computational and Systems Biology
    2. Neuroscience

    Metabolic activity organizes olfactory representations

    Wesley W Qian, Jennifer N Wei ... Alexander B Wiltschko
    Metabolic activity across all living things represents an organizing principle for the sense of smell in humans and animals.
    1. Neuroscience

    Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

    Michelle M Frank, Austen A Sitko ... Lisa V Goodrich
    Single-nucleus sequencing, anatomy, and physiology reveal heterogeneity among olivocochlear neurons (a group of cells that provide feedback to the inner ear), identify a neuropeptide-enriched subtype, and show that neuropeptide expression changes during postnatal development and after sound exposure.
    1. Cell Biology
    2. Neuroscience

    Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2

    Sang Hwa Kim, Kye D Nichols ... Randal S Tibbetts
    Axon guidance genes are conserved regulators of neurodegeneration in Drosophila melanogaster and human inducible motor neuron models of UBQLN2-associated amyotrophic lateral sclerosis.
    1. Developmental Biology
    2. Neuroscience

    Lifelong regeneration of cerebellar Purkinje cells after induced cell ablation in zebrafish

    Sol Pose-Méndez, Paul Schramm ... Reinhard W Köster
    Purkinje cell-specific ablation demonstrates regeneration of these neurons and functional recovery of the cerebellum during both larval and adult zebrafish.
    1. Neuroscience

    NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice

    Ruolin Zhang, Weibing Mao ... Zhiqiang Dong
    The combination of NSCs with NSC-derived exosomes ameliorated the injury of brain tissue including cerebral infarction, neuronal death, and glial scarring, and promoted the recovery of motor function.
    1. Neuroscience

    Oligodendrocyte-mediated myelin plasticity and its role in neural synchronization

    Sinisa Pajevic, Dietmar Plenz ... R Douglas Fields
    A biologically plausible model of myelin plasticity demonstrates how oligodendrocytes can selectively adjust conduction delays in axon bundles to allow robust communication between brain regions through long-range synchronization.
    1. Cell Biology
    2. Neuroscience

    Activity regulates a cell type-specific mitochondrial phenotype in zebrafish lateral line hair cells

    Andrea McQuate, Sharmon Knecht, David W Raible
    The highly metabolically active hair cells of the zebrafish lateral line have a distinct mitochondrial phenotype consisting of small mitochondria apically and large, networked mitochondrion basally, demonstrating a nonuniform mitochondrial architecture that is sculpted by cellular activity.
    1. Neuroscience

    Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention

    Amélie Aussel, Ian C Fiebelkorn ... Benjamin Rafael Pittman-Polletta
    A biophysical cortical circuit model reveals how thalamic inputs mediate complex dynamics in the frontal eye fields and lateral intraparietal area, enabling rhythmic enhancements in visual sensitivity observed behaviorally.
    1. Neuroscience

    Differential ripple propagation along the hippocampal longitudinal axis

    Roberto De Filippo, Dietmar Schmitz
    Ripple origination point shapes neural activity dynamics across the different hippocampal subfields.
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain

    Siân Wilson, Maximilian Pietsch ... Tomoki Arichi
    Using fetal magnetic resonance imaging (MRI), maturational changes in tissue microstructure can be derived using diffusion MRI which provide new insight into the fundamental neurobiological transitions occurring within the emerging thalamocortical white matter pathways.