Browse our latest Neuroscience articles

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    1. Neuroscience

    Theta-phase-specific modulation of dentate gyrus memory neurons

    Bahar Rahsepar, Jacob F Norman ... John A White
    Consistent with an existing computational model of hippocampal function, using real-time feedback to drive artificial memories at the trough of the hippocampal theta rhythm improves apparent recall.
    1. Neuroscience

    Recapitulation of pathophysiological features of AD in SARS-CoV-2-infected subjects

    Elizabeth Griggs, Kyle Trageser ... Giulio Maria Pasinetti
    New evidence of brain proinflammatory cascades supports post-acute sequelae of SARS-CoV-2 infection, ultimately promoting the onset and progression of Alzheimer's disease as a function of age.
    1. Computational and Systems Biology
    2. Neuroscience

    Contrasting action and posture coding with hierarchical deep neural network models of proprioception

    Kai J Sandbrink, Pranav Mamidanna ... Alexander Mathis
    To isolate and study proprioception, hierarchical deep neural networks paired with biomechanical models provide a normative approach to test the role of task effects on neural representations, such as the emergence of kinematic tuning and higher-level abstractions of actions.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Rubella virus tropism and single-cell responses in human primary tissue and microglia-containing organoids

    Galina Popova, Hanna Retallack ... Tomasz Nowakowski
    Combination of primary brain culture and single-cell RNA sequencing in brain organoids identifies microglia as the main target of rubella virus infection.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Neuroscience

    Rate-distortion theory of neural coding and its implications for working memory

    Anthony MV Jakob, Samuel J Gershman
    The abstract framework of rate-distortion theory can be realized by a neural population coding model to reproduce key and previously unexplained regularities of human visual working memory.
    1. Neuroscience

    Nested circuits mediate the decision to vocalize

    Shuyun Xiao, Valerie Michael, Richard Mooney
    The decision to vocalize depends on neural circuits that balance the rewards of potential social affiliation with the risks of advertising.
    1. Neuroscience

    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

    Yuzo Fujino, Morio Ueyama ... Yoshitaka Nagai
    Alteration of the G-quadruplex structure formed by GGGGCC repeat RNA through the direct interaction with RNA-binding proteins can suppress pathogenic repeat-associated non-AUG translation, leading to therapeutic effects on neurodegeneration in C9orf72-linked amyotrophic lateral sclerosis and frontotemporal dementia.
    1. Neuroscience

    Prefrontal cortex state representations shape human credit assignment

    Amrita Lamba, Matthew R Nassar, Oriel FeldmanHall
    The medial prefrontal cortex and orbitofrontal cortex work in concert to match state representations from feedback to those at choice, and the strength of these common neural codes predict credit assignment precision.
    1. Neuroscience

    Disentangled multi-subject and social behavioral representations through a constrained subspace variational autoencoder (CS-VAE)

    Daiyao Yi, Simon Musall ... Shreya Saxena
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Rapid, automated, and experimenter-free touchscreen testing reveals reciprocal interactions between cognitive flexibility and activity-based anorexia in female rats

    Kaixin Huang, Laura K Milton ... Claire J Foldi
    An automated touchscreen cognitive testing system for rats reduces the length of training required to learn tasks, making it possible to assess cognitive profiles in adolescent animals to more appropriately capture cognitive deficits in adolescent pathologies, such as anorexia nervosa.