Browse our latest Neuroscience articles

Page 223 of 599
    1. Neuroscience

    Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection

    Murat Kilinc, Vineet Arora ... Gavin Rumbaugh
    Alternatively spliced C-terminal protein sequences encoded by the Syngap1 gene exhibit unique biochemical and functional properties in vivo, which explain in part how individual isoforms can promote cognitive functions and seizure protection.
    1. Cell Biology
    2. Neuroscience

    Long-range migration of centrioles to the apical surface of the olfactory epithelium

    Kaitlin Ching, Jennifer T Wang, Tim Stearns
    Olfactory sensory neurons have centrioles that are amplified in number and that migrate from the cell body to the end of the dendrite relatively slowly and in groups, becoming mature only after they reach their destination.
    1. Neuroscience

    Independent and interacting value systems for reward and information in the human brain

    Irene Cogliati Dezza, Axel Cleeremans, William H Alexander
    Reward and information are independently optimized in the human prefrontal cortex, while their signals combine in subcortical regions.
    1. Neuroscience

    Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum

    Zhihui Liu, Man Jiang ... Thomas C Südhof
    Calsyntenin-3 functions in cerebellar Purkinje neurons as a postsynaptic adhesion molecule that, unexpectedly, suppresses excitatory parallel-fiber synapse numbers but boosts inhibitory synapse numbers and thereby controls the excitatory/inhibitory balance of Purkinje neurons.
    1. Neuroscience

    Task-related hemodynamic responses in human early visual cortex are modulated by task difficulty and behavioral performance

    Charlie S Burlingham, Minyoung Ryoo ... Elisha P Merriam
    The fMRI-BOLD signal in human early visual cortex reflects alertness and behavioral performance on the timescale of individual trials.
    1. Neuroscience

    Neuronal origins of reduced accuracy and biases in economic choices under sequential offers

    Weikang Shi, Sebastien Ballesta, Camillo Padoa-Schioppa
    Neuronal activity in the primate orbitofrontal cortex reveals different choice biases observed when offers are presented sequentially originate at different stages of the decision process.
    1. Neuroscience

    The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice

    Han Zhang, Natalia A Shevtsova ... Ilya A Rybak
    The role of genetically identified V3 interneurons with ascending propriospinal projections in the spinal locomotor circuitry and their contribution to the limb coordination and speed-dependent gait expression during locomotion were investigated using a combination of experimental studies and computational modeling.
    1. Neuroscience

    Learning: The devil is in the task structure

    Orit Nafcha, Uri Hertz
    Conflicting evidence about how the brain processes social and individual learning stems from which type of information is presented as the primary source of knowledge during experiments.
    Version of Record
    Insight
    1. Neuroscience

    Drosulfakinin signaling modulates female sexual receptivity in Drosophila

    Tao Wang, Biyang Jing ... Chuan Zhou
    The neuropeptide Drosulfakinin (DSK) functions in a subset of DSK neurons to interact with neural nodes in the sex circuit and acts through its receptor CCKLR-17D3 to control female sexual behavior.
    1. Neuroscience

    Hippocampal-hypothalamic circuit controls context-dependent innate defensive responses

    Jee Yoon Bang, Julia Kathryn Sunstrum ... Junchul Kim
    The hippocampus controls context-dependent defensive behaviors through the anterior hypothalamus, a major component of the medial hypothalamic defense system, by retrieving contextual information essential for avoiding predatory threats and escaping to a safe shelter.