Browse our latest Neuroscience articles

Transportomic analysis of the changes underlying neurodegeneration reveals the importance of Kif5a for neuronal survival and highlights the need to restore specific anterograde cargo transport to for regeneration.

TIGAR deficiency in cholinergic neuron enhanced intracellular acetyl-CoA levels and pyruvate dehydrogenase flux into the TCA cycle that drives increased cholinergic tone with reduced heart rate and blood pressure and raised resistance against the paralytic curare and cold-induced hypothermia.

In vitro and in vivo physiological analyses reveal that mammalian auditory neuron intrinsic mechanical sensitivity contributes to sound-evoked activity and explains other previously unexplained auditory neuron features.

A novel pathway from the deep entorhinal cortex to the hippocampus suggests that the hippocampal–neocortical loop is supported by a feedback projection from the entorhinal deep layers that copies entorhinal output to the hippocampus.

Molecular, genetic, and behavioral assays in mice establish a new role for Hox proteins in the final steps of spinal motor neuron development.

Retinoic acid signaling from Muller glia is necessary for cone photoreceptor survival in the peripheral retina and is sufficient to promote cone survival in the central retina during retinal degeneration.

Shank promotes functional coupling between CaV1 calcium channels and BK potassium channels.

Responses to odour mixtures are more discriminable in awake, behaving mice due to a combination of dampened responses keeping responses in the linear range and pattern decorrelation, with these two mechanisms operating on different timescales.

The higher order thalamus encodes and influences correct action during learning and performance in a sensory-based goal-directed behavior.

Through associative learning, environmental context can come to exert control over the endogenous opioid system such that it is recruited as a conditioned compensatory response to ongoing painful stimuli in both male and female mice, or in anticipation of a painful stimulus in females.